Xianming Zhang

  • 158 Citations
20082019
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Research Output 2008 2019

  • 158 Citations
  • 15 Article
  • 1 Chapter
  • 1 Review article
2019

Endothelial Hypoxia-Inducible Factor-1α Is Required for Vascular Repair and Resolution of Inflammatory Lung Injury through Forkhead Box Protein M1

Huang, X., Zhang, X., Zhao, D. X., Yin, J., Hu, G., Evans, C. E. & Zhao, Y., Aug 1 2019, In : American Journal of Pathology. 189, 8, p. 1664-1679 16 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Lung Injury
Blood Vessels
Sepsis
Endothelial Cells
4 Citations (Scopus)

Ephrin receptor A4 is a new kaposi’s sarcoma-associated herpesvirus virus entry receptor

Chen, J., Zhang, X., Schaller, S., Jardetzky, T. S. & Longnecker, R. M., Jan 1 2019, In : mBio. 10, 1, e02892-18.

Research output: Contribution to journalArticle

Open Access
EphA4 Receptor
Ephrin-A2
Virus Receptors
Satellite Viruses
Human Herpesvirus 8
2018

Endothelial and Smooth Muscle Cell Interaction via FoxM1 Signaling Mediates Vascular Remodeling and Pulmonary Hypertension

Dai, Z., Zhu, MM., Peng, Y., Jin, H., Qian, Z., Zhang, X. & Zhao, YY., Sep 15 2018, In : Am J Respir Crit Care Med. 198, 6, p. 788-802 15 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Ephrin receptor A2 is a functional entry receptor for Epstein-Barr virus

Chen, J., Sathiyamoorthy, K., Zhang, X., Schaller, S., Perez-White, B. E., Jardetzky, T. S. & Longnecker, R. M., Feb 1 2018, In : Nature Microbiology. 3, 2, p. 172-180 9 p.

Research output: Contribution to journalArticle

Ephrin-A2
Complement 3d Receptors
Eph Family Receptors
Human Herpesvirus 4
Epithelial Cells

Ephrin receptor A2 is a functional entry receptor for Epstein–Barr virus

Chen, J., Sathiyamoorthy, K., Zhang, X., Schaller, S., Perez, W. BE., Jardetzky, TS. & Longnecker, R., Feb 2018, In : Nat Microbiol. 3, 2, p. 172-180 9 p.

Research output: Contribution to journalArticle

Therapeutic Targeting of Vascular Remodeling and Right Heart Failure in PAH with HIF-2a Inhibitor

Dai, Z., Zhu, MM., Peng, Y., Machireddy, N., Evans, CE., Machado, R., Zhang, X. & Zhao, YY., Jun 20 2018, In : Am J Respir Crit Care Med.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Therapeutic Targeting of Vascular Remodeling and Right Heart Failure in PAH with HIF-2α Inhibitor

Dai, Z., Zhu, M. M., Peng, Y., Machireddy, N., Evans, C. E., Machado, R., Zhang, X. & Zhao, Y-Y., Jun 20 2018, In : American Journal of Respiratory and Critical Care Medicine.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Heart Failure
Lung
Monocrotaline
Rodentia
2017

Lipopolysaccharide-induced endotoxemia in corn oil-preloaded mice causes an extended course of lung injury and repair and pulmonary fibrosis: A translational mouse model of acute respiratory distress syndrome

Wu, C., Evans, CE., Dai, Z., Huang, X., Zhang, X., Jin, H., Hu, G., Song, Y. & Zhao, YY., Mar 23 2017, In : PLoS One. 12, 3, p. 174327 1 p.

Research output: Contribution to journalArticle

2015
7 Citations (Scopus)

Downregulation of kinin B1 receptor function by B2 receptor heterodimerization and signaling

Zhang, X., Brovkovych, V., Zhang, Y., Tan, F. & Skidgel, R. A., Jan 1 2015, In : Cellular Signalling. 27, 1, p. 90-103 14 p.

Research output: Contribution to journalArticle

Kinins
Endocytosis
Down-Regulation
G-Protein-Coupled Receptors
Electric Impedance
2014
2 Citations (Scopus)

Germacranes and m-menthane from illicium lanceolatum

Zhao, M., Zhang, X., Wang, Y., Huang, M., Duan, J. A., Gödecke, T., Szymulanska-Ramamurthy, K. M., Yin, Z. & Che, C. T., Jan 1 2014, In : Molecules. 19, 4, p. 4326-4337 12 p.

Research output: Contribution to journalArticle

Open Access
Germacrane Sesquiterpenes
Illicium
Pimpinella
trienes
Monoterpenes
11 Citations (Scopus)
Human herpesvirus 4
Virus Internalization
Human Herpesvirus 4
energy requirements
glycoproteins
2013
6 Citations (Scopus)

Carboxypeptidase M

Zhang, X. & Skidgel, R. A., Aug 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd., Vol. 1. p. 1357-1366 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

carboxypeptidase M
12 Citations (Scopus)

Carboxypeptidase M augments kinin B1 receptor signaling by conformational crosstalk and enhances endothelial nitric oxide output

Zhang, X., Tan, F., Brovkovych, V., Zhang, Y., Lowry, J. L. & Skidgel, R. A., Mar 1 2013, In : Biological Chemistry. 394, 3, p. 335-345 11 p.

Research output: Contribution to journalReview article

Kallidin
Kinins
Bradykinin
Crosstalk
G-Protein-Coupled Receptors
16 Citations (Scopus)

Carboxypeptidase M is a positive allosteric modulator of the kinin B1 receptor

Zhang, X., Tan, F. & Skidgel, R. A., Nov 15 2013, In : Journal of Biological Chemistry. 288, 46, p. 33226-33240 15 p.

Research output: Contribution to journalArticle

Open Access
Kinins
Modulators
Kallidin
Phosphatidylinositols
carboxypeptidase M
2012
5 Citations (Scopus)

Characterization of dual agonists for kinin B1 and B2 receptors and their biased activation of B2 receptors

Zhang, X., Lowry, J. L., Brovkovych, V. & Skidgel, R. A., Aug 1 2012, In : Cellular Signalling. 24, 8, p. 1619-1631 13 p.

Research output: Contribution to journalArticle

Kallidin
Kinins
Bradykinin
Phosphorylation
Endothelial Cells
2011
23 Citations (Scopus)

Cross-talk between carboxypeptidase M and the kinin B1 receptor mediates a new mode of G protein-coupled receptor signaling

Zhang, X., Tan, F., Brovkovych, V., Zhang, Y. & Skidgel, R. A., May 27 2011, In : Journal of Biological Chemistry. 286, 21, p. 18547-18561 15 p.

Research output: Contribution to journalArticle

Open Access
Kinins
G-Protein-Coupled Receptors
Bradykinin
Kallidin
Fluorescence Resonance Energy Transfer
2008
40 Citations (Scopus)

Carboxypeptidase M and kinin B1 receptors interact to facilitate efficient B1 signaling from B2 agonists

Zhang, X., Tan, F., Zhang, Y. & Skidgel, R. A., Mar 21 2008, In : Journal of Biological Chemistry. 283, 12, p. 7994-8004 11 p.

Research output: Contribution to journalArticle

Open Access
Kinins
Bradykinin
Kallidin
Cyclodextrins
carboxypeptidase M