Xianming Zhang

  • 179 Citations
20082019
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Research Output 2008 2019

  • 179 Citations
  • 14 Article
  • 1 Chapter
  • 1 Review article
2019

Endothelial Hypoxia-Inducible Factor-1α Is Required for Vascular Repair and Resolution of Inflammatory Lung Injury through Forkhead Box Protein M1

Huang, X., Zhang, X., Zhao, D. X., Yin, J., Hu, G., Evans, C. E. & Zhao, Y., Aug 1 2019, In : American Journal of Pathology. 189, 8, p. 1664-1679 16 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Lung Injury
Blood Vessels
Sepsis
Endothelial Cells
5 Citations (Scopus)

Ephrin receptor A4 is a new kaposi’s sarcoma-associated herpesvirus virus entry receptor

Chen, J., Zhang, X., Schaller, S., Jardetzky, T. S. & Longnecker, R. M., Jan 1 2019, In : mBio. 10, 1, e02892-18.

Research output: Contribution to journalArticle

Open Access
EphA4 Receptor
Ephrin-A2
Virus Receptors
Satellite Viruses
Human Herpesvirus 8
2018
14 Citations (Scopus)

Endothelial and smooth muscle cell interaction via FoxM1 signaling mediates vascular remodeling and pulmonary hypertension

Dai, Z., Zhu, M. M., Peng, Y., Jin, H., Machireddy, N., Qian, Z., Zhang, X. & Zhao, Y. Y., Sep 15 2018, In : American journal of respiratory and critical care medicine. 198, 6, p. 788-802 15 p.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Cell Communication
Smooth Muscle Myocytes
Endothelial Cells
Cell Proliferation
33 Citations (Scopus)

Ephrin receptor A2 is a functional entry receptor for Epstein-Barr virus

Chen, J., Sathiyamoorthy, K., Zhang, X., Schaller, S., Perez-White, B. E., Jardetzky, T. S. & Longnecker, R. M., Feb 1 2018, In : Nature Microbiology. 3, 2, p. 172-180 9 p.

Research output: Contribution to journalArticle

Ephrin-A2
Complement 3d Receptors
Eph Family Receptors
Human Herpesvirus 4
Epithelial Cells

Ephrin receptor A2 is a functional entry receptor for Epstein–Barr virus

Chen, J., Sathiyamoorthy, K., Zhang, X., Schaller, S., Perez, W. BE., Jardetzky, TS. & Longnecker, R., Feb 2018, In : Nat Microbiol. 3, 2, p. 172-180 9 p.

Research output: Contribution to journalArticle

Therapeutic Targeting of Vascular Remodeling and Right Heart Failure in PAH with HIF-2a Inhibitor

Dai, Z., Zhu, MM., Peng, Y., Machireddy, N., Evans, CE., Machado, R., Zhang, X. & Zhao, YY., Jun 20 2018, In : Am J Respir Crit Care Med.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Therapeutic Targeting of Vascular Remodeling and Right Heart Failure in PAH with HIF-2α Inhibitor

Dai, Z., Zhu, M. M., Peng, Y., Machireddy, N., Evans, C. E., Machado, R., Zhang, X. & Zhao, Y-Y., Jun 20 2018, In : American Journal of Respiratory and Critical Care Medicine.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Heart Failure
Lung
Monocrotaline
Rodentia
2015
7 Citations (Scopus)

Downregulation of kinin B1 receptor function by B2 receptor heterodimerization and signaling

Zhang, X., Brovkovych, V., Zhang, Y., Tan, F. & Skidgel, R. A., Jan 1 2015, In : Cellular Signalling. 27, 1, p. 90-103 14 p.

Research output: Contribution to journalArticle

Kinins
Endocytosis
Down-Regulation
G-Protein-Coupled Receptors
Electric Impedance
2014
2 Citations (Scopus)

Germacranes and m-menthane from illicium lanceolatum

Zhao, M., Zhang, X., Wang, Y., Huang, M., Duan, J. A., Gödecke, T., Szymulanska-Ramamurthy, K. M., Yin, Z. & Che, C. T., Apr 2014, In : Molecules. 19, 4, p. 4326-4337 12 p.

Research output: Contribution to journalArticle

Open Access
Germacrane Sesquiterpenes
Illicium
Pimpinella
trienes
Monoterpenes
12 Citations (Scopus)
Human herpesvirus 4
Virus Internalization
Human Herpesvirus 4
energy requirements
glycoproteins
2013
6 Citations (Scopus)

Carboxypeptidase M

Zhang, X. & Skidgel, R. A., Aug 29 2013, Handbook of Proteolytic Enzymes. Elsevier Ltd., Vol. 1. p. 1357-1366 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

carboxypeptidase M
12 Citations (Scopus)

Carboxypeptidase M augments kinin B1 receptor signaling by conformational crosstalk and enhances endothelial nitric oxide output

Zhang, X., Tan, F., Brovkovych, V., Zhang, Y., Lowry, J. L. & Skidgel, R. A., Mar 1 2013, In : Biological Chemistry. 394, 3, p. 335-345 11 p.

Research output: Contribution to journalReview article

Kallidin
Kinins
Bradykinin
Crosstalk
G-Protein-Coupled Receptors
16 Citations (Scopus)

Carboxypeptidase M is a positive allosteric modulator of the kinin B1 receptor

Zhang, X., Tan, F. & Skidgel, R. A., Nov 15 2013, In : Journal of Biological Chemistry. 288, 46, p. 33226-33240 15 p.

Research output: Contribution to journalArticle

Open Access
Kinins
Modulators
Kallidin
Phosphatidylinositols
carboxypeptidase M
2012
5 Citations (Scopus)

Characterization of dual agonists for kinin B1 and B2 receptors and their biased activation of B2 receptors

Zhang, X., Lowry, J. L., Brovkovych, V. & Skidgel, R. A., Aug 1 2012, In : Cellular Signalling. 24, 8, p. 1619-1631 13 p.

Research output: Contribution to journalArticle

Kallidin
Kinins
Bradykinin
Phosphorylation
Endothelial Cells
2011
23 Citations (Scopus)

Cross-talk between carboxypeptidase M and the kinin B1 receptor mediates a new mode of G protein-coupled receptor signaling

Zhang, X., Tan, F., Brovkovych, V., Zhang, Y. & Skidgel, R. A., May 27 2011, In : Journal of Biological Chemistry. 286, 21, p. 18547-18561 15 p.

Research output: Contribution to journalArticle

Open Access
Kinins
G-Protein-Coupled Receptors
Bradykinin
Kallidin
Fluorescence Resonance Energy Transfer
2008
40 Citations (Scopus)

Carboxypeptidase M and kinin B1 receptors interact to facilitate efficient B1 signaling from B2 agonists

Zhang, X., Tan, F., Zhang, Y. & Skidgel, R. A., Mar 21 2008, In : Journal of Biological Chemistry. 283, 12, p. 7994-8004 11 p.

Research output: Contribution to journalArticle

Open Access
Kinins
Bradykinin
Kallidin
Cyclodextrins
carboxypeptidase M