Grants per year
Personal profile
Research Interests
Development of novel patient derived orthotopic xenograft mouse models, understand tumor biology and identify new diagnostic and/or therapeutic targets, perform comprehensive preclinical drug testing to establish preclinical rational for the initiation of clinical trials.
Nonn.
Training Experience
| 1990 | Residency, Suzhou Medical College/Soochow University, PR.China |
| 1992 | Fellowship, Suzhou Medical College/Soochow University, PR.China |
| 2001 | Postdoctoral Fellowship, Baylor College Of Medicine |
Education/Academic qualification
PhD, Tumor Biology, Suzhou Medical College/Soochow University
… → 1993
MD, Radiation Medicine, Suzhou Medical College/Soochow University
… → 1985
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Collaborations and top research areas from the last five years
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Grants
- 1 Active
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CCSG/DTC Resource
Li, X.-N. (Co-Investigator) & Li, X.-N. (Co-Investigator)
8/1/23 → 7/31/25
Project: Research project
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CD57 defines a novel cancer stem cell that drive invasion of diffuse pediatric-type high grade gliomas
Qi, L., Du, Y., Huang, Y., Kogiso, M., Zhang, H., Xiao, S., Abdallah, A., Suarez, M., Niu, L., Liu, Z. G., Lindsay, H., Braun, F. K., Stephen, C., Davies, P. J., Teo, W. Y., Adenkunle, A., Baxter, P., Su, J. M. F. & Li, X. N., Jul 22 2024, In: British Journal of Cancer. 131, 2, p. 258-270 13 p.Research output: Contribution to journal › Article › peer-review
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Direct Implantation of Patient Brain Tumor Cells into Matching Locations in Mouse Brains for Patient-Derived Orthotopic Xenograft Model Development
Qi, L., Baxter, P., Kogiso, M., Zhang, H., Braun, F. K., Lindsay, H., Zhao, S., Xiao, S., Abdallah, A. S., Suarez, M., Huang, Z., Teo, W. Y., Yu, L., Zhao, X., Liu, Z., Huang, Y., Su, J. M., Man, T. K., Lau, C. C. & Perlaky, L. & 2 others, , May 2024, In: Cancers. 16, 9, 1716.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Fractionated radiation therapy alters energy metabolism and induces cellular quiescence exit in patient-derived orthotopic xenograft models of high-grade glioma
Huang, Z. L., Liu, Z. G., Lin, Q., Tao, Y. L., Li, X., Baxter, P., Su, J. M., Adesina, A. M., Man, C., Chintagumpala, M., Teo, W. Y., Du, Y. C., Xia, Y. F. & Li, X. N., Jul 2024, In: Translational Oncology. 45, 101988.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Lessons learned from 20 years of preclinical testing in pediatric cancers
Smith, M. A., Houghton, P. J., Lock, R. B., Maris, J. M., Gorlick, R., Kurmasheva, R. T., Li, X. N., Teicher, B. A., Chuang, J. H., Dela Cruz, F. S., Dyer, M. A., Kung, A. L., Lloyd, M. W., Mossé, Y. P., Stearns, T. M., Stewart, E. A., Bult, C. J. & Erickson, S. W., Dec 2024, In: Pharmacology and Therapeutics. 264, 108742.Research output: Contribution to journal › Review article › peer-review
Open Access -
Patient-Derived Models of Cancer in the NCI PDMC Consortium: Selection, Pitfalls, and Practical Recommendations
Habowski, A. N., Budagavi, D. P., Scherer, S. D., Aurora, A. B., Caligiuri, G., Flynn, W. F., Langer, E. M., Brody, J. R., Sears, R. C., Foggetti, G., Arnal Estape, A., Nguyen, D. X., Politi, K. A., Shen, X., Hsu, D. S., Peehl, D. M., Kurhanewicz, J., Sriram, R., Suarez, M. & Xiao, S. & 5 others, , Feb 2024, In: Cancers. 16, 3, 565.Research output: Contribution to journal › Review article › peer-review
Open Access