Xiao-Qi Wang

Personal profile

Research Interests

I have been investigated the function of glycolipid on skin cell behavior, including skin cancers and poor wound healing. I have also focused on the delivery of nanoconjugates to skin cells and mice skin in the hope of developing better strategies to target poor wound healing and abnormal scar formation.

Bench based investigation

Education/Academic qualification

MD, PhD, Dalian University

… → 1991

Research interests

Cancer Biology
Cell Adhesion Mechanisms
Cell Biology
Cutaneous Biology
Dermatology
Molecular Biology
Oncology
Skin Cancer

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Gangliosides Medicine & Life Sciences

G(M3) Ganglioside Medicine & Life Sciences

Fucosyltransferases Medicine & Life Sciences

Epidermal Growth Factor Receptor Medicine & Life Sciences

Phosphorylation Chemical Compounds

Integrins Medicine & Life Sciences

Cell Proliferation Medicine & Life Sciences

Chemical activation Chemical Compounds

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Grants 2004 2021

2 Active
9 Finished

Glycosphingolipids Mediate Diabetic Wound Healing Impairment

Paller, A. & Wang, X.

National Institute of Arthritis and Musculoskeletal and Skin Diseases

5/1/16 → 4/30/21

Project: Research project

Somatomedin Receptors

Glycosphingolipids

Wound Healing

Keratinocytes

Membrane Microdomains

Self-Management of Abnormal Scars with Spherical Nucleic Acid Technology

Mirkin, C. A., Paller, A. & Wang, X.

Nanyang Technological University

11/1/14 → 10/31/20

Project: Research project

Self Care

Nucleic Acids

Cicatrix

Technology

Hypertrophic Cicatrix

Ultra-Small Nanoparticle-Based Platform for Photodynamic Skin Cancer Therapy

Paller, A. & Wang, X.

Nanyang Technological University

11/1/14 → 10/31/17

Project: Research project

Skin Neoplasms

Nanoparticles

Silicon Dioxide

Photochemotherapy

Neoplasms

Topical delivery of keratin 10 mutation-specific siRNA-gold nanoparticles for epidermolytic ichthyosis

Mirkin, C. A., Paller, A. & Wang, X.

Foundation for Ichthyosis & Related Skin Types

9/1/12 → 8/31/14

Project: Research project

Topical Delivery of siRNA Nanoconjugates: Suppressing Epidermal Hyperplasia

Mirkin, C. A., Paller, A. & Wang, X.

National Institute of Arthritis and Musculoskeletal and Skin Diseases

3/1/12 → 2/28/17

Project: Research project

Research Output 2001 2018

1773 Citations
47 Article
1 Review article

2 Citations (Scopus)

Emerging roles of ozone in skin diseases

Wang, X., Feb 2018, In : Journal of Central South University (Medical Sciences). 43, 2, p. 114-123 10 p.

Research output: Contribution to journal › Article

Ozone

Skin Diseases

Therapeutic Uses

Skin

Infectious Skin Diseases

7 Citations (Scopus)

Ganglioside GM3 Mediates Glucose-Induced Suppression of IGF-1 Receptor–Rac1 Activation to Inhibit Keratinocyte Motility

Dam, D. H. M., Wang, X. Q., Sheu, S., Vijay, M., Shipp, D., Miller, L. & Paller, A. S., Feb 1 2017, In : Journal of Investigative Dermatology. 137, 2, p. 440-448 9 p.

Research output: Contribution to journal › Article

G(M3) Ganglioside

IGF Type 1 Receptor

Somatomedins

Keratinocytes

Chemical activation

4 Citations (Scopus)

Novel function of pregnancy-associated plasma protein A: Promotes endometrium receptivity by up-regulating N-fucosylation

Yu, M., Wang, J., Liu, S., Wang, X-Q. & Yan, Q., Dec 1 2017, In : Scientific Reports. 7, 1, 5315.

Research output: Contribution to journal › Article

Pregnancy-Associated Plasma Protein-A

Endometrium

Trophoblasts

Pregnant Women

Biomarkers

10 Citations (Scopus)

Topically Delivered Tumor Necrosis Factor-α–Targeted Gene Regulation for Psoriasis

Lewandowski, K. T., Thiede, R., Guido, N., Daniel, W. L., Kang, R., Guerrero-Zayas, M. I., Seeger, M. A., Wang, X-Q., Giljohann, D. A. & Paller, A., Sep 1 2017, In : Journal of Investigative Dermatology. 137, 9, p. 2027-2030 4 p.

Research output: Contribution to journal › Article

Gene expression

Animals

Tumor Necrosis Factor-alpha

DNA

5 Citations (Scopus)

Ganglioside GM3 synthase depletion reverses neuropathic pain and small fiber neuropathy in diet-induced diabetic mice

Menichella, D. M., Jayaraj, N. D., Wilson, H. M., Ren, D., Flood, K., Wang, X. Q., Shum, A., Miller, R. J. & Paller, A. S., Aug 1 2016, In : Molecular Pain. 12

Research output: Contribution to journal › Article

Diabetic Diet

G(M3) Ganglioside

Neuralgia

Wound Healing

Obese Mice