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Xiaonan Li

  • 3065 Citations
1992 …2020

Research output per year

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Personal profile

Research Interests

Development of novel patient derived orthotopic xenograft mouse models, understand tumor biology and identify new diagnostic and/or therapeutic targets, perform comprehensive preclinical drug testing to establish preclinical rational for the initiation of clinical trials.

Nonn.

Training Experience

1990Residency, Suzhou Medical College/Soochow University, PR.China
1992Fellowship, Suzhou Medical College/Soochow University, PR.China
2001Postdoctoral Fellowship, Baylor College Of Medicine

Education/Academic qualification

PhD, Suzhou Medical College/Soochow University

… → 1993

MD, Suzhou Medical College/Soochow University

… → 1985

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Grants

DTC Shared Resource

James, C. D. & Li, X.

National Cancer Institute

8/10/18 → 7/31/23

Project: Research project

    • LCH Subaward

    Li, X. & Platanias, L. C.

    National Cancer Institute

    8/10/18 → 7/31/23

    Project: Research project

    • Research Output

    • 3065 Citations
    • 81 Article
    • 2 Comment/debate
    • 1 Review article

    Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth

    Yao, M., Ventura, P. B., Jiang, Y., Rodriguez, F. J., Wang, L., Perry, J. S. A., Yang, Y., Wahl, K., Crittenden, R. B., Bennett, M. L., Qi, L., Gong, C. C., Li, X. N., Barres, B. A., Bender, T. P., Ravichandran, K. S., Janes, K. A., Eberhart, C. G. & Zong, H., Feb 6 2020, In : Cell. 180, 3, p. 502-520.e19

    Research output: Contribution to journal › Article

    • 5 Scopus citations

    Mislocalized cytoplasmic p27 activates PAK1-mediated metastasis and is a prognostic factor in osteosarcoma

    Chen, X., Cates, J. M. M., Du, Y. C., Jain, A., Jung, S. Y., Li, X. N., Hicks, J. M. & Man, T. K., Apr 1 2020, In : Molecular oncology. 14, 4, p. 846-864 19 p.

    Research output: Contribution to journal › Article

    Open Access

    • Patient-derived orthotopic xenograft (PDOX) mouse models of primary and recurrent meningioma

    Zhang, H., Qi, L., Du, Y., Huang, L. F., Braun, F. K., Kogiso, M., Zhao, Y., Li, C., Lindsay, H., Zhao, S., Injac, S. G., Baxter, P. A., Su, J. M., Stephan, C., Keller, C., Heck, K. A., Harmanci, A., Harmanci, A. O., Yang, J., Klisch, T. J. & 2 others, Li, X. N. & Patel, A. J., Jun 2020, In : Cancers. 12, 6, p. 1-17 17 p., 1478.

    Research output: Contribution to journal › Article

    Open Access

    • A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor

    Sin-Chan, P., Mumal, I., Suwal, T., Ho, B., Fan, X., Singh, I., Du, Y., Lu, M., Patel, N., Torchia, J., Popovski, D., Fouladi, M., Guilhamon, P., Hansford, J. R., Leary, S., Hoffman, L. M., Mulcahy Levy, J. M., Lassaletta, A., Solano-Paez, P., Rivas, E. & 34 others, Reddy, A., Gillespie, G. Y., Gupta, N., Van Meter, T. E., Nakamura, H., Wong, T. T., Ra, Y. S., Kim, S. K., Massimi, L., Grundy, R. G., Fangusaro, J., Johnston, D., Chan, J., Lafay-Cousin, L., Hwang, E. I., Wang, Y., Catchpoole, D., Michaud, J., Ellezam, B., Ramanujachar, R., Lindsay, H., Taylor, M. D., Hawkins, C. E., Bouffet, E., Jabado, N., Singh, S. K., Kleinman, C. L., Barsyte-Lovejoy, D., Li, X. N., Dirks, P. B., Lin, C. Y., Mack, S. C., Rich, J. N. & Huang, A., Jul 8 2019, In : Cancer Cell. 36, 1, p. 51-67.e7

    Research output: Contribution to journal › Article

    • 11 Scopus citations

    Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design

    Rokita, J. L., Rathi, K. S., Cardenas, M. F., Upton, K. A., Jayaseelan, J., Cross, K. L., Pfeil, J., Egolf, L. E., Way, G. P., Farrel, A., Kendsersky, N. M., Patel, K., Gaonkar, K. S., Modi, A., Berko, E. R., Lopez, G., Vaksman, Z., Mayoh, C., Nance, J., McCoy, K. & 49 others, Haber, M., Evans, K., McCalmont, H., Bendak, K., Böhm, J. W., Marshall, G. M., Tyrrell, V., Kalletla, K., Braun, F. K., Qi, L., Du, Y., Zhang, H., Lindsay, H. B., Zhao, S., Shu, J., Baxter, P., Morton, C., Kurmashev, D., Zheng, S., Chen, Y., Bowen, J., Bryan, A. C., Leraas, K. M., Coppens, S. E., Doddapaneni, H. V., Momin, Z., Zhang, W., Sacks, G. I., Hart, L. S., Krytska, K., Mosse, Y. P., Gatto, G. J., Sanchez, Y., Greene, C. S., Diskin, S. J., Vaske, O. M., Haussler, D., Gastier-Foster, J. M., Kolb, E. A., Gorlick, R., Li, X. N., Reynolds, C. P., Kurmasheva, R. T., Houghton, P. J., Smith, M. A., Lock, R. B., Raman, P., Wheeler, D. A. & Maris, J. M., Nov 5 2019, In : Cell reports. 29, 6, p. 1675-1689.e9

    Research output: Contribution to journal › Article

    Open Access
    • 5 Scopus citations