Xiaonan Li

  • 2950 Citations
1992 …2023

Research output per year

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Personal profile

Research Interests

Development of novel patient derived orthotopic xenograft mouse models, understand tumor biology and identify new diagnostic and/or therapeutic targets, perform comprehensive preclinical drug testing to establish preclinical rational for the initiation of clinical trials.

Nonn.

Training Experience

1990Residency, Suzhou Medical College/Soochow University, PR.China
1992Fellowship, Suzhou Medical College/Soochow University, PR.China
2001Postdoctoral Fellowship, Baylor College Of Medicine

Education/Academic qualification

PhD, Suzhou Medical College/Soochow University

… → 1993

MD, Suzhou Medical College/Soochow University

… → 1985

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Grants

LCH Subaward

Platanias, L. C. & Li, X.

National Cancer Institute

8/10/187/31/23

Project: Research project

  • DTC Shared Resource

    James, C. D. & Li, X.

    National Cancer Institute

    8/10/187/31/23

    Project: Research project

  • Research Output

    • 2950 Citations
    • 78 Article
    • 2 Comment/debate
    • 1 Review article

    A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor

    Sin-Chan, P., Mumal, I., Suwal, T., Ho, B., Fan, X., Singh, I., Du, Y., Lu, M., Patel, N., Torchia, J., Popovski, D., Fouladi, M., Guilhamon, P., Hansford, J. R., Leary, S., Hoffman, L. M., Mulcahy Levy, J. M., Lassaletta, A., Solano-Paez, P., Rivas, E. & 34 others, Reddy, A., Gillespie, G. Y., Gupta, N., Van Meter, T. E., Nakamura, H., Wong, T. T., Ra, Y. S., Kim, S. K., Massimi, L., Grundy, R. G., Fangusaro, J., Johnston, D., Chan, J., Lafay-Cousin, L., Hwang, E. I., Wang, Y., Catchpoole, D., Michaud, J., Ellezam, B., Ramanujachar, R., Lindsay, H., Taylor, M. D., Hawkins, C. E., Bouffet, E., Jabado, N., Singh, S. K., Kleinman, C. L., Barsyte-Lovejoy, D., Li, X. N., Dirks, P. B., Lin, C. Y., Mack, S. C., Rich, J. N. & Huang, A., Jul 8 2019, In : Cancer Cell. 36, 1, p. 51-67.e7

    Research output: Contribution to journalArticle

  • 6 Scopus citations

    Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design

    Rokita, J. L., Rathi, K. S., Cardenas, M. F., Upton, K. A., Jayaseelan, J., Cross, K. L., Pfeil, J., Egolf, L. E., Way, G. P., Farrel, A., Kendsersky, N. M., Patel, K., Gaonkar, K. S., Modi, A., Berko, E. R., Lopez, G., Vaksman, Z., Mayoh, C., Nance, J., McCoy, K. & 49 others, Haber, M., Evans, K., McCalmont, H., Bendak, K., Böhm, J. W., Marshall, G. M., Tyrrell, V., Kalletla, K., Braun, F. K., Qi, L., Du, Y., Zhang, H., Lindsay, H. B., Zhao, S., Shu, J., Baxter, P., Morton, C., Kurmashev, D., Zheng, S., Chen, Y., Bowen, J., Bryan, A. C., Leraas, K. M., Coppens, S. E., Doddapaneni, H. V., Momin, Z., Zhang, W., Sacks, G. I., Hart, L. S., Krytska, K., Mosse, Y. P., Gatto, G. J., Sanchez, Y., Greene, C. S., Diskin, S. J., Vaske, O. M., Haussler, D., Gastier-Foster, J. M., Kolb, E. A., Gorlick, R., Li, X. N., Reynolds, C. P., Kurmasheva, R. T., Houghton, P. J., Smith, M. A., Lock, R. B., Raman, P., Wheeler, D. A. & Maris, J. M., Nov 5 2019, In : Cell reports. 29, 6, p. 1675-1689.e9

    Research output: Contribution to journalArticle

    Open Access
  • 4 Scopus citations

    Relevance of a TCGA-derived Glioblastoma Subtype Gene-Classifier among Patient Populations

    Teo, W. Y., Sekar, K., Seshachalam, P., Shen, J., Chow, W. Y., Lau, C. C., Yang, H. K., Park, J., Kang, S. G., Li, X., Nam, D. H. & Hui, K. M., Dec 1 2019, In : Scientific reports. 9, 1, 7442.

    Research output: Contribution to journalArticle

    Open Access
  • 3 Scopus citations

    Resolving medulloblastoma cellular architecture by single-cell genomics

    Hovestadt, V., Smith, K. S., Bihannic, L., Filbin, M. G., Shaw, M. K. L., Baumgartner, A., DeWitt, J. C., Groves, A., Mayr, L., Weisman, H. R., Richman, A. R., Shore, M. E., Goumnerova, L., Rosencrance, C., Carter, R. A., Phoenix, T. N., Hadley, J. L., Tong, Y., Houston, J., Ashmun, R. A. & 31 others, DeCuypere, M., Sharma, T., Flasch, D., Silkov, A., Ligon, K. L., Pomeroy, S. L., Rivera, M. N., Rozenblatt-Rosen, O., Rusert, J. M., Wechsler-Reya, R. J., Li, X. N., Peyrl, A., Gojo, J., Kirchhofer, D., Lötsch, D., Czech, T., Dorfer, C., Haberler, C., Geyeregger, R., Halfmann, A., Gawad, C., Easton, J., Pfister, S. M., Regev, A., Gajjar, A., Orr, B. A., Slavc, I., Robinson, G. W., Bernstein, B. E., Suvà, M. L. & Northcott, P. A., Aug 1 2019, In : Nature. 572, 7767, p. 74-79 6 p.

    Research output: Contribution to journalArticle

  • 18 Scopus citations

    The molecular landscape of ETMR at diagnosis and relapse

    Lambo, S., Gröbner, S. N., Rausch, T., Waszak, S. M., Schmidt, C., Gorthi, A., Romero, J. C., Mauermann, M., Brabetz, S., Krausert, S., Buchhalter, I., Koster, J., Zwijnenburg, D. A., Sill, M., Hübner, J. M., Mack, N., Schwalm, B., Ryzhova, M., Hovestadt, V., Papillon-Cavanagh, S. & 45 others, Chan, J. A., Landgraf, P., Ho, B., Milde, T., Witt, O., Ecker, J., Sahm, F., Sumerauer, D., Ellison, D. W., Orr, B. A., Darabi, A., Haberler, C., Figarella-Branger, D., Wesseling, P., Schittenhelm, J., Remke, M., Taylor, M. D., Gil-da-Costa, M. J., Łastowska, M., Grajkowska, W., Hasselblatt, M., Hauser, P., Pietsch, T., Uro-Coste, E., Bourdeaut, F., Masliah-Planchon, J., Rigau, V., Alexandrescu, S., Wolf, S., Li, X. N., Schüller, U., Snuderl, M., Karajannis, M. A., Giangaspero, F., Jabado, N., von Deimling, A., Jones, D. T. W., Korbel, J. O., von Hoff, K., Lichter, P., Huang, A., Bishop, A. J. R., Pfister, S. M., Korshunov, A. & Kool, M., Dec 12 2019, In : Nature. 576, 7786, p. 274-280 7 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations