Xiaonan Li

  • 2672 Citations
1992 …2019
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Personal profile

Research Interests

Development of novel patient derived orthotopic xenograft mouse models, understand tumor biology and identify new diagnostic and/or therapeutic targets, perform comprehensive preclinical drug testing to establish preclinical rational for the initiation of clinical trials.

Nonn.

Training Experience

1990Residency, Suzhou Medical College/Soochow University, PR.China
1992Fellowship, Suzhou Medical College/Soochow University, PR.China
2001Postdoctoral Fellowship, Baylor College Of Medicine

Education/Academic qualification

PhD, Suzhou Medical College/Soochow University

… → 1993

MD, Suzhou Medical College/Soochow University

… → 1985

Fingerprint Dive into the research topics where Xiaonan Li is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 12 Similar Profiles
Medulloblastoma Medicine & Life Sciences
Glioma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Heterografts Medicine & Life Sciences
Pediatrics Medicine & Life Sciences
Glioblastoma Medicine & Life Sciences
Neoplastic Stem Cells Medicine & Life Sciences
Brain Neoplasms Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1992 2019

  • 2672 Citations
  • 76 Article
  • 2 Comment/debate
  • 1 Review article
1 Citation (Scopus)

A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor

Sin-Chan, P., Mumal, I., Suwal, T., Ho, B., Fan, X., Singh, I., Du, Y., Lu, M., Patel, N., Torchia, J., Popovski, D., Fouladi, M., Guilhamon, P., Hansford, J. R., Leary, S., Hoffman, L. M., Mulcahy Levy, J. M., Lassaletta, A., Solano-Paez, P., Rivas, E. & 34 others, Reddy, A., Gillespie, G. Y., Gupta, N., Van Meter, T. E., Nakamura, H., Wong, T. T., Ra, Y. S., Kim, S. K., Massimi, L., Grundy, R. G., Fangusaro, J., Johnston, D., Chan, J., Lafay-Cousin, L., Hwang, E. I., Wang, Y., Catchpoole, D., Michaud, J., Ellezam, B., Ramanujachar, R., Lindsay, H., Taylor, M. D., Hawkins, C. E., Bouffet, E., Jabado, N., Singh, S. K., Kleinman, C. L., Barsyte-Lovejoy, D., Li, X., Dirks, P. B., Lin, C. Y., Mack, S. C., Rich, J. N. & Huang, A., Jul 8 2019, In : Cancer Cell. 36, 1, p. 51-67.e7

Research output: Contribution to journalArticle

MicroRNAs
Brain Neoplasms
Neoplasms
Cell Death
Therapeutics

Relevance of a TCGA-derived Glioblastoma Subtype Gene-Classifier among Patient Populations

Teo, W. Y., Sekar, K., Seshachalam, P., Shen, J., Chow, W. Y., Lau, C. C., Yang, H. K., Park, J., Kang, S. G., Li, X., Nam, D. H. & Hui, K. M., Dec 1 2019, In : Scientific reports. 9, 1, 7442.

Research output: Contribution to journalArticle

Open Access
Glioblastoma
temozolomide
Population
Genes
Heterografts
1 Citation (Scopus)

Resolving medulloblastoma cellular architecture by single-cell genomics

Hovestadt, V., Smith, K. S., Bihannic, L., Filbin, M. G., Shaw, M. K. L., Baumgartner, A., DeWitt, J. C., Groves, A., Mayr, L., Weisman, H. R., Richman, A. R., Shore, M. E., Goumnerova, L., Rosencrance, C., Carter, R. A., Phoenix, T. N., Hadley, J. L., Tong, Y., Houston, J., Ashmun, R. A. & 31 others, DeCuypere, M., Sharma, T., Flasch, D., Silkov, A., Ligon, K. L., Pomeroy, S. L., Rivera, M. N., Rozenblatt-Rosen, O., Rusert, J. M., Wechsler-Reya, R. J., Li, X., Peyrl, A., Gojo, J., Kirchhofer, D., Lötsch, D., Czech, T., Dorfer, C., Haberler, C., Geyeregger, R., Halfmann, A., Gawad, C., Easton, J., Pfister, S. M., Regev, A., Gajjar, A., Orr, B. A., Slavc, I., Robinson, G. W., Bernstein, B. E., Suvà, M. L. & Northcott, P. A., Aug 1 2019, In : Nature. 572, 7767, p. 74-79 6 p.

Research output: Contribution to journalArticle

Medulloblastoma
Genomics
Neoplasms
Cerebellar Neoplasms
Population Groups
2 Citations (Scopus)

Transcriptional repressor REST drives lineage stage-specific chromatin compaction at Ptch1 and increases AKT activation in a mouse model of medulloblastoma

Dobson, T. H. W., Tao, R. H., Swaminathan, J., Maegawa, S., Shaik, S., Bravo-Alegria, J., Sharma, A., Kennis, B., Yang, Y., Callegari, K., Haltom, A. R., Taylor, P., Kogiso, M., Qi, L., Khatua, S., Goldman, S., Lulla, R. R., Fangusaro, J., MacDonald, T. J., Li, X. & 3 others, Hawkins, C., Rajaram, V. & Gopalakrishnan, V., Jan 22 2019, In : Science Signaling. 12, 565, aan8680.

Research output: Contribution to journalArticle

Medulloblastoma
Hedgehogs
Chromatin
Compaction
Chemical activation
2 Citations (Scopus)

Concurrent inhibition of neurosphere and monolayer cells of pediatric glioblastoma by aurora a inhibitor mln8237 predicted survival extension in pdox models

Kogiso, M., Qi, L., Braun, F. K., Injac, S. G., Zhang, L., Du, Y., Zhang, H., Lin, F. Y., Zhao, S., Lindsay, H., Su, J. M., Baxter, P. A., Adesina, A. M., Liao, D., Qian, M. G., Berg, S., Muscal, J. A. & Li, X. N., May 1 2018, In : Clinical Cancer Research. 24, 9, p. 2159-2170 12 p.

Research output: Contribution to journalArticle

Aurora Kinase A
Glioblastoma
Pediatrics
Survival
Heterografts