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Dive into the research topics where Xiaoyu Zhang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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A Molecular Approach to Dissecting MEK-Mediated Phosphorylation in Pediatric Leukemia
Scheidt, K. A. (PD/PI), Schiltz, G. E. (PD/PI) & Zhang, X. (Co-Investigator)
5/15/24 → 4/30/29
Project: Research project
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Discovering and developing neoantigen inducers as new and effective cancer immunotherapeutics
Zhang, X. (PD/PI)
Dr. Ralph and Marian Falk Medical Research Trust
2/28/23 → 2/28/25
Project: Research project
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Discovering and developing antigen modifiers as new and effective cancer immunotherapeutics
Zhang, X. (PD/PI)
10/1/22 → 9/30/25
Project: Research project
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Discovery of Small Molecule-Mediated Protein Degradation Pathways in Human Cancer
Zhang, X. (PD/PI) & Zhang, X. (PD/PI)
2/1/22 → 1/31/25
Project: Research project
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A Universal Approach to Drive the Immune Recognition of Cancer Cells
Zhang, X. (PD/PI)
1/1/22 → 12/31/24
Project: Research project
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Inhibiting the Keap1/Nrf2 Protein-Protein Interaction with Protein-Like Polymers
Carrow, K. P., Hamilton, H. L., Hopps, M. P., Li, Y., Qiao, B., Payne, N. C., Thompson, M. P., Zhang, X., Magassa, A., Fattah, M., Agarwal, S., Vincent, M. P., Buyanova, M., Bertin, P. A., Mazitschek, R., Olvera de la Cruz, M., Johnson, D. A., Johnson, J. A. & Gianneschi, N. C., May 23 2024, In: Advanced Materials. 36, 21, 2311467.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Erratum: Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1 (Journal of the American Chemical Society (2022) 144: 40 (18688−186990) DOI: 10.1021/jacs.2c08964)
Tao, Y., Remillard, D., Vinogradova, E. V., Yokoyama, M., Banchenko, S., Schwefel, D., Melillo, B., Schreiber, S. L., Zhang, X. & Cravatt, B. F., Jun 14 2023, In: Journal of the American Chemical Society. 145, 23, p. 12948 1 p.Research output: Contribution to journal › Comment/debate › peer-review
1 Scopus citations -
Rational Design of Highly Potent and Selective Covalent MAP2K7 Inhibitors
Kim, D. R., Orr, M. J., Kwong, A. J., Deibler, K. K., Munshi, H. H., Bridges, C. S., Chen, T. J., Zhang, X., Lacorazza, H. D. & Scheidt, K. A., May 11 2023, In: ACS Medicinal Chemistry Letters. 14, 5, p. 606-613 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A Proteomic Approach Identifies Isoform-Specific and Nucleotide-Dependent RAS Interactions
Miller, S. P., Maio, G., Zhang, X., Badillo Soto, F. S., Zhu, J., Ramirez, S. Z. & Lin, H., Aug 2022, In: Molecular and Cellular Proteomics. 21, 8, 100268.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Insights and Future Perspectives of Covalent Protein Degraders
Zhang, X., Jan 1 2022, Inducing Targeted Protein Degradation: from Chemical Biology to Drug Discovery and Clinical Applications. wiley, p. 215-243 29 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations
Datasets
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Structure of Human NMT1 with products CoA and myristoyl-lysine peptide with acetylated N-terminus
Kosciuk, T. (Contributor), Price, I. R. (Contributor), Zhang, X. (Contributor), Zhu, C. (Contributor), Johnson, K. N. (Contributor), Zhang, S. (Contributor), Halaby, S. L. (Contributor), Komaniecki, G. P. (Contributor), Yang, M. (Contributor), DeHart, C. J. (Contributor), Thomas, P. M. (Contributor), Kelleher, N. L. (Contributor), Christopher Fromme, F. J. (Contributor) & Lin, H. (Contributor), Protein Data Bank (PDB), Mar 11 2020
DOI: 10.2210/pdb6PAV, https://www.wwpdb.org/pdb?id=pdb_00006pav
Dataset
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Structure of Human NMT2 with myristoyl-lysine peptide and CoA products
Kosciuk, T. (Contributor), Price, I. R. (Contributor), Zhang, X. (Contributor), Zhu, C. (Contributor), Johnson, K. N. (Contributor), Zhang, S. (Contributor), Halaby, S. L. (Contributor), Komaniecki, G. P. (Contributor), Yang, M. (Contributor), DeHart, C. J. (Contributor), Thomas, P. M. (Contributor), Kelleher, N. L. (Contributor), Christopher Fromme, F. J. (Contributor) & Lin, H. (Contributor), Protein Data Bank (PDB), Mar 11 2020
DOI: 10.2210/pdb6PAU, https://www.wwpdb.org/pdb?id=pdb_00006pau
Dataset