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Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Xiaoyu Zhang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Chemical proteomic mapping and functional manipulation of extracellular proteinaceous cysteines
Zhang, X. (PD/PI)
National Institute of General Medical Sciences
9/15/24 → 8/31/29
Project: Research project
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A Molecular Approach to Dissecting MEK-Mediated Phosphorylation in Pediatric Leukemia
Scheidt, K. A. (PD/PI), Schiltz, G. E. (PD/PI) & Zhang, X. (Co-Investigator)
5/15/24 → 4/30/29
Project: Research project
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Discovering and developing neoantigen inducers as new and effective cancer immunotherapeutics
Zhang, X. (PD/PI) & Zhang, X. (PD/PI)
Dr. Ralph and Marian Falk Medical Research Trust
2/28/23 → 2/28/26
Project: Research project
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Discovering and developing antigen modifiers as new and effective cancer immunotherapeutics
Zhang, X. (PD/PI)
10/1/22 → 9/30/25
Project: Research project
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Discovery of Chemical Probes that Support Targeted Protein Degradation in Human Cancer
Zhang, X. (PD/PI)
Damon Runyon Cancer Research Foundation
3/1/22 → 2/29/24
Project: Research project
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Covalent targeting of splicing in T cells
Scott, K. A., Kojima, H., Ropek, N., Warren, C. D., Zhang, T. L., Hogg, S. J., Sanford, H., Webster, C., Zhang, X., Rahman, J., Melillo, B., Cravatt, B. F., Lyu, J., Abdel-Wahab, O. & Vinogradova, E. V., Jan 16 2025, In: Cell Chemical Biology. 32, 1, p. 201-218.e17Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Discovery of DCAF16 Binders for Targeted Protein Degradation
Campos, M. A., Riha, I. A., Zhang, C., Mozes, C., Scheidt, K. A. & Zhang, X., Feb 21 2025, In: ACS chemical biology. 20, 2, p. 479-488 10 p.Research output: Contribution to journal › Article › peer-review
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Harnessing the FBXW7 Somatic Mutant R465C for Targeted Protein Degradation
Basu, A. A., Zhang, C., Rouhimoghadam, M., Vasudevan, A., Reitsma, J. M. & Zhang, X., Feb 19 2025, In: Journal of the American Chemical Society. 147, 7, p. 6108-6115 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Implications of frequent hitter E3 ligases in targeted protein degradation screens
Zhang, X., Simon, G. M. & Cravatt, B. F., Apr 2025, In: Nature Chemical Biology. 21, 4, p. 474-481 8 p., 679120.Research output: Contribution to journal › Article › peer-review
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Protein-Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction
Mesfin, J. M., Carrow, K. P., Chen, A., Hopps, M. P., Holm, J. J. J., Lyons, Q. P., Nguyen, M. B., Hunter, J. D., Magassa, A., Wong, E. G., Reimold, K., Paleti, S. N., Gardner, E., Thompson, M. P., Luo, C. G., Zhang, X., Christman, K. L. & Gianneschi, N. C., 2025, (Accepted/In press) In: Advanced Materials.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Structure of Human NMT2 with myristoyl-lysine peptide and CoA products
Kosciuk, T. (Contributor), Price, I. R. (Contributor), Zhang, X. (Contributor), Zhu, C. (Contributor), Johnson, K. N. (Contributor), Zhang, S. (Contributor), Halaby, S. L. (Contributor), Komaniecki, G. P. (Contributor), Yang, M. (Contributor), DeHart, C. J. (Contributor), Thomas, P. M. (Contributor), Kelleher, N. L. (Contributor), Christopher, F. J. (Contributor) & Lin, H. (Contributor), Protein Data Bank (PDB), Mar 11 2020
DOI: 10.2210/pdb6PAU/pdb, https://www.wwpdb.org/pdb?id=pdb_00006pau
Dataset
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Structure of Human NMT1 with products CoA and myristoyl-lysine peptide with acetylated N-terminus
Kosciuk, T. (Contributor), Price, I. R. (Contributor), Zhang, X. (Contributor), Zhu, C. (Contributor), Johnson, K. N. (Contributor), Zhang, S. (Contributor), Halaby, S. L. (Contributor), Komaniecki, G. P. (Contributor), Yang, M. (Contributor), DeHart, C. J. (Contributor), Thomas, P. M. (Contributor), Kelleher, N. L. (Contributor), Christopher, F. J. (Contributor) & Lin, H. (Contributor), Protein Data Bank (PDB), Mar 11 2020
DOI: 10.2210/pdb6PAV/pdb, https://www.wwpdb.org/pdb?id=pdb_00006pav
Dataset