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Personal profile

Research Interests

Professor Wang's laboratory is interested in the regulatory mechanisms that control cell-fate decision during development in mammals. They combine genomic and genetic approaches to investigate how microRNAs and chromatin regulators influence gene expression in embryonic stem cells. They also study how Pcdh signaling pathway regulates the survival of spinal interneurons.

Education/Academic qualification

Cell Biology, PhD, New York University

… → 1997

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  • Research Output

    • 10072 Citations
    • 49 Article
    • 2 Chapter
    • 1 Review article

    Tumor heterogeneity and clonal cooperation influence the immune selection of IFN-γ-signaling mutant cancer cells

    Williams, J. B., Li, S., Higgs, E. F., Cabanov, A., Wang, X., Huang, H. & Gajewski, T. F., Dec 1 2020, In : Nature communications. 11, 1, 602.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron

    Cedernaes, J., Huang, W., Ramsey, K. M., Waldeck, N., Cheng, L., Marcheva, B., Omura, C., Kobayashi, Y., Peek, C. B., Levine, D. C., Dhir, R., Awatramani, R., Bradfield, C. A., Wang, X. A., Takahashi, J. S., Mokadem, M., Ahima, R. S. & Bass, J., May 7 2019, In : Cell Metabolism. 29, 5, p. 1078-1091.e5

    Research output: Contribution to journalArticle

  • 17 Scopus citations

    The cyclic phosphodiesterase CNP and RNA cyclase RtcA fine-tune noncanonical XBP1 splicing during ER stress

    Unlu, I., Lu, Y. & Wang, X., Jan 1 2018, In : Journal of Biological Chemistry. 293, 50, p. 19365-19376 12 p.

    Research output: Contribution to journalArticle

  • 5 Scopus citations

    A recessive genetic screen for components of the RNA interference pathway performed in mouse embryonic stem cells

    Trombly, M. I. & Wang, X., Jan 1 2017, Methods in Molecular Biology. Humana Press Inc, p. 111-129 19 p. (Methods in Molecular Biology; vol. 1622).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins

    Bridge, K. S., Shah, K. M., Li, Y., Foxler, D. E., Wong, S. C. K., Miller, D. C., Davidson, K. M., Foster, J. G., Rose, R., Hodgkinson, M. R., Ribeiro, P. S., Aboobaker, A. A., Yashiro, K., Wang, X., Graves, P. R., Plevin, M. J., Lagos, D. & Sharp, T. V., Jul 5 2017, In : Cell reports. 20, 1, p. 173-187 15 p.

    Research output: Contribution to journalArticle

  • 21 Scopus citations