Xinxin Song

  • 938 Citations
20072022
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Personal profile

Research Interests

The role of ubiquitin-proteasome system in carcinogenesis, cell death, and drug resistance in breast cancer

Education/Academic qualification

PhD, Peking Union Medical College

… → 2010

MD, Peking University

… → 2005

Fingerprint Dive into the research topics where Xinxin Song is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Grants 2017 2022

Breast Neoplasms
Neoplasm Metastasis
Genes
Early Diagnosis
Proteins
Estrogens
Carcinogenesis
Tamoxifen
Breast Neoplasms
Ubiquitin-Protein Ligases
Carcinogenesis
Methylation
Breast Neoplasms
Breast
Ubiquitination

Research Output 2007 2018

  • 938 Citations
  • 24 Article
  • 1 Letter
  • 1 Review article
24 Citations (Scopus)

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc Activity

Song, X., Zhu, S., Chen, P., Hou, W., Wen, Q., Liu, J., Xie, Y., Liu, J., Klionsky, D. J., Kroemer, G., Lotze, M. T., Zeh, H. J., Kang, R. & Tang, D., Aug 6 2018, In : Current Biology. 28, 15, p. 2388-2399.e5

Research output: Contribution to journalArticle

AMP-activated protein kinase
Phosphorylation
AMP-Activated Protein Kinases
Lipid Peroxidation
phosphorylation
8 Citations (Scopus)

Crosstalk between apoptosis and autophagy is regulated by the arginylated BiP/Beclin-1/p62 complex

Song, X., Lee, D. H., Dilly, A. K., Lee, Y. S., Choudry, H. A., Kwon, Y. T., Bartlett, D. L. & Lee, Y. J., Jul 1 2018, In : Molecular Cancer Research. 16, 7, p. 1077-1091 15 p.

Research output: Contribution to journalArticle

Autophagy
Apoptosis
Mitomycin
Heterografts
Colorectal Neoplasms
10 Citations (Scopus)

JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice

Song, X., Zhu, S., Xie, Y., Liu, J., Sun, L., Zeng, D., Wang, P., Ma, X., Kroemer, G., Bartlett, D. L., Billiar, T. R., Lotze, M. T., Zeh, H. J., Kang, R. & Tang, D., Apr 1 2018, In : Gastroenterology. 154, 5, p. 1480-1493 14 p.

Research output: Contribution to journalArticle

Growth
Neoplasms
Cell Death
Cell Line
Adenocarcinoma
1 Citation (Scopus)

PARK7 modulates autophagic proteolysis through binding to the N-terminally arginylated form of the molecular chaperone HSPA5

Lee, D. H., Kim, D., Kim, S. T., Jeong, S., Kim, J. L., Shim, S. M., Heo, A. J., Song, X., Guo, Z. S., Bartlett, D. L., Oh, S. C., Lee, J., Saito, Y., Kim, B. Y., Kwon, Y. T. & Lee, Y. J., Nov 2 2018, In : Autophagy. 14, 11, p. 1870-1885 16 p.

Research output: Contribution to journalArticle

Molecular Chaperones
Proteolysis
Autophagy
Ubiquitin
Proteins
56 Citations (Scopus)

The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity

Xie, Y., Zhu, S., Song, X., Sun, X., Fan, Y., Liu, J., Zhong, M., Yuan, H., Zhang, L., Billiar, T. R., Lotze, M. T., Zeh, H. J., Kang, R., Kroemer, G. & Tang, D., Aug 15 2017, In : Cell Reports. 20, 7, p. 1692-1704 13 p.

Research output: Contribution to journalArticle

Dipeptidyl Peptidase 4
Tumors
Transcription
Neoplasms
Precision Medicine