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Yinan Zheng

  • 709 Citations
20122020

Research output per year

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Personal profile

Research Interests

Dr. Zheng’s research focuses on identifying epigenomic biomarkers linking environmental exposures and lifestyle behaviors (including air pollution, diet, and physical activity) with various aging-related disease development (including cancer, cardiovascular diseases, and dementia) using data generated from population cohorts and clinical trials. Dr. Zheng specializes in developing bioinformatics software for high-dimensional epigenomic data and conducting bioinformatics analysis using omics/systems biology-based approaches. His recent work has begun to explore the role of methylation in cardiovascular risks/diseases and in virus-associated cancers.

Education/Academic qualification

PhD, Northwestern University, Feinberg School of Medicine

… → 2017

MS, Northwestern University, Feinberg School of Medicine

… → 2012

Research interests

  • Aging
  • Bioinformatics
  • Cancer Biology
  • Cardiovascular Diseases
  • Epigenetics
  • Systems Biology

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Grants

Epigenetic Determinants of Lipoproteins Across the Early Adult Life Course

Allen, N. B., Hou, L., Lloyd-Jones, D. M., Wilkins, J. T., Zhao, L. & Zheng, Y.

National Heart, Lung, and Blood Institute

3/1/20 → 2/29/24

Project: Research project

Associations Between Whole Genome Sequencing-Derived Telomere Length and Subclinical Cardiovascular Disease: The Coronary Artery Risk Development in Young Adults (CARDIA) Study

Hou, L., Lloyd-Jones, D. M. & Zheng, Y.

American Heart Association

7/1/19 → 6/30/22

Project: Research project

    • Longitudinal epigenomic study of gestational diabetes mellitus and cardiac structure and function

    Hou, L., Lloyd-Jones, D. M., Wang, J. & Zheng, Y.

    American Heart Association

    7/1/19 → 6/30/21

    Project: Research project

    Research Output

    • 709 Citations
    • 46 Article
    • 1 Comment/debate

    Biomarkers of aging and lung function in the normative aging study

    Wang, C., Just, A., Heiss, J., Coull, B. A., Hou, L., Zheng, Y., Sparrow, D., Vokonas, P. S., Baccarelli, A. & Schwartz, J., Jun 30 2020, In : Aging. 12, 12, p. 11942-11966 25 p.

    Research output: Contribution to journal › Article

    • Ca:Mg Ratio, APOE Cytosine Modifications, and Cognitive Function: Results from a Randomized Trial

    Zhu, X., Borenstein, A. R., Zheng, Y., Zhang, W., Seidner, D. L., Ness, R., Murff, H. J., Li, B., Shrubsole, M. J., Yu, C., Hou, L. & Dai, Q., 2020, In : Journal of Alzheimer's Disease. 75, 1, p. 85-98 14 p.

    Research output: Contribution to journal › Article

    • Epigenomic analysis of 5-hydroxymethylcytosine (5hmC) reveals novel DNA methylation markers for lung cancers

    Wang, Z., Du, M., Yuan, Q., Guo, Y., Hutchinson, J. N., Su, L., Zheng, Y., Wang, J., Mucci, L. A., Lin, X., Hou, L. & Christiani, D. C., Mar 2020, In : Neoplasia (United States). 22, 3, p. 154-161 8 p.

    Research output: Contribution to journal › Article

    Open Access

    • Prenatal gestational diabetes mellitus exposure and accelerated offspring DNA methylation age in early childhood

    Shiau, S., Wang, L., Liu, H., Zheng, Y., Drong, A., Joyce, B. T., Wang, J., Li, W., Leng, J., Shen, Y., Gao, R., Hu, G., Hou, L. & Baccarelli, A. A., 2020, In : Epigenetics.

    Research output: Contribution to journal › Article

    • A peripheral blood DNA methylation signature of hepatic fat reveals a potential causal pathway for nonalcoholic fatty liver disease

    Ma, J., Nano, J., Ding, J., Zheng, Y., Hennein, R., Liu, C., Speliotes, E. K., Huan, T., Song, C., Mendelson, M. M., Joehanes, R., Long, M. T., Liang, L., Smith, J. A., Reynolds, L. M., Ghanbari, M., Muka, T., Van Meurs, J. B. J., Alferink, L. J. M., Franco, O. H. & 17 others, Dehghan, A., Ratliff, S., Zhao, W., Bielak, L., Kardia, S. L. R., Peyser, P. A., Ning, H., VanWagner, L. B., Lloyd-Jones, D. M., Carr, J. J., Greenland, P., Lichtenstein, A. H., Hu, F. B., Liu, Y., Hou, L., Murad, S. D. & Levy, D., Jan 1 2019, In : Diabetes. 68, 5, p. 1073-1083 11 p.

    Research output: Contribution to journal › Article

    • 5 Scopus citations