Grants per year
Personal profile
Research Interests
Dr. Zheng’s research focuses on identifying epigenomic biomarkers linking environmental exposures and lifestyle behaviors (including air pollution, diet, and physical activity) with various aging-related disease development (including cancer, cardiovascular diseases, and dementia) using data generated from population cohorts and clinical trials. Dr. Zheng specializes in developing bioinformatics software for high-dimensional epigenomic data and conducting bioinformatics analysis using omics/systems biology-based approaches. His recent work has begun to explore the role of methylation in cardiovascular risks/diseases and in virus-associated cancers.
Education/Academic qualification
PhD, Northwestern University, Feinberg School of Medicine
… → 2017
Biomedical Informatics, PhD, Northwestern University, Feinberg School of Medicine
… → 2017
MS, Northwestern University, Feinberg School of Medicine
… → 2012
Epidemiology and Biostatistics , MS, Northwestern University, Feinberg School of Medicine
… → 2012
Research interests
- Aging
- Bioinformatics
- Cancer Biology
- Cardiovascular Diseases
- Epigenetics
- Systems Biology
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Grants
- 5 Active
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The Fragile Families Cardiovascular Health Follow Up Study
Allen, N. B., Hou, L., Lloyd-Jones, D. M., Zheng, Y. & Van Horn, L.
Princeton University, National Heart, Lung, and Blood Institute
8/1/20 → 7/31/24
Project: Research project
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Blood mitochondrial DNA biomarkers of midlife cognitive decline and adverse brain imaging changes – A longitudinal investigation in the CARDIA population‐based cohort study.
Hou, L., Wang, J., Zheng, Y. & Gao, T.
Columbia University, National Institute on Aging
7/15/20 → 4/30/25
Project: Research project
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Epigenetic Determinants of Lipoproteins Across the Early Adult Life Course
Allen, N. B., Hou, L., Lloyd-Jones, D. M., Wilkins, J. T., Zhao, L. & Zheng, Y.
National Heart, Lung, and Blood Institute
3/1/20 → 2/29/24
Project: Research project
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Longitudinal epigenomic study of gestational diabetes mellitus and cardiac structure and function
Hou, L., Lloyd-Jones, D. M., Wang, J., Zheng, Y. & Joyce, B.
7/1/19 → 6/30/21
Project: Research project
Research Output
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Association of the V122I Transthyretin Amyloidosis Genetic Variant with Cardiac Structure and Function in Middle-Aged Black Adults: Coronary Artery Risk Development in Young Adults (CARDIA) Study
Sinha, A., Zheng, Y., Nannini, D., Qu, Y., Hou, L., Shah, S. J., Yancy, C. W., McNally, E. M., Fornage, M., Lima, J., Lloyd-Jones, D. M., Rasmussen-Torvik, L. J. & Khan, S. S., 2020, (Accepted/In press) In: JAMA cardiology.Research output: Contribution to journal › Article › peer-review
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Associations of smoking and air pollution with peripheral blood RNA N6-methyladenosine in the Beijing truck driver air pollution study
Kupsco, A., Gonzalez, G., Baker, B. H., Knox, J. M., Zheng, Y., Wang, S., Chang, D., Schwartz, J., Hou, L., Wang, Y. & Baccarelli, A. A., Nov 2020, In: Environment International. 144, 106021.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Biomarkers of aging and lung function in the normative aging study
Wang, C., Just, A., Heiss, J., Coull, B. A., Hou, L., Zheng, Y., Sparrow, D., Vokonas, P. S., Baccarelli, A. & Schwartz, J., Jun 30 2020, In: Aging. 12, 12, p. 11942-11966 25 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Ca:Mg Ratio, APOE Cytosine Modifications, and Cognitive Function: Results from a Randomized Trial
Zhu, X., Borenstein, A. R., Zheng, Y., Zhang, W., Seidner, D. L., Ness, R., Murff, H. J., Li, B., Shrubsole, M. J., Yu, C., Hou, L. & Dai, Q., 2020, In: Journal of Alzheimer's Disease. 75, 1, p. 85-98 14 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Epigenomic analysis of 5-hydroxymethylcytosine (5hmC) reveals novel DNA methylation markers for lung cancers
Wang, Z., Du, M., Yuan, Q., Guo, Y., Hutchinson, J. N., Su, L., Zheng, Y., Wang, J., Mucci, L. A., Lin, X., Hou, L. & Christiani, D. C., Mar 2020, In: Neoplasia (United States). 22, 3, p. 154-161 8 p.Research output: Contribution to journal › Article › peer-review
Open Access