Grants per year
Personal profile
Research Interests
Dr. Zheng’s research focuses on identifying epigenomic biomarkers linking environmental exposures and lifestyle behaviors (including air pollution, diet, and physical activity) with various aging-related disease development (including cancer, cardiovascular diseases, and dementia) using data generated from population cohorts and clinical trials. Dr. Zheng specializes in developing bioinformatics software for high-dimensional epigenomic data and conducting bioinformatics analysis using omics/systems biology-based approaches. His recent work has begun to explore the role of methylation in cardiovascular risks/diseases and in virus-associated cancers.
Education/Academic qualification
PhD, Northwestern University Feinberg School of Medicine
… → 2017
MS, Northwestern University Feinberg School of Medicine
… → 2012
Research interests
- Aging
- Bioinformatics
- Cancer Biology
- Cardiovascular Diseases
- Epigenetics
- Systems Biology
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Grants
- 3 Active
Epigenetic Determinants of Lipoproteins Across the Early Adult Life Course
Allen, N. B., Hou, L., Lloyd-Jones, D. M., Wilkins, J. T., Zhao, L. & Zheng, Y.
National Heart, Lung, and Blood Institute
3/1/20 → 2/29/24
Project: Research project
Longitudinal epigenomic study of gestational diabetes mellitus and cardiac structure and function
Hou, L., Lloyd-Jones, D. M., Wang, J. & Zheng, Y.
7/1/19 → 6/30/21
Project: Research project
Research Output
Epigenomic analysis of 5-hydroxymethylcytosine (5hmC) reveals novel DNA methylation markers for lung cancers
Wang, Z., Du, M., Yuan, Q., Guo, Y., Hutchinson, J. N., Su, L., Zheng, Y., Wang, J., Mucci, L. A., Lin, X., Hou, L. & Christiani, D. C., Mar 2020, In : Neoplasia (United States). 22, 3, p. 154-161 8 p.Research output: Contribution to journal › Article
Open Access
A peripheral blood DNA methylation signature of hepatic fat reveals a potential causal pathway for nonalcoholic fatty liver disease
Ma, J., Nano, J., Ding, J., Zheng, Y., Hennein, R., Liu, C., Speliotes, E. K., Huan, T., Song, C., Mendelson, M. M., Joehanes, R., Long, M. T., Liang, L., Smith, J. A., Reynolds, L. M., Ghanbari, M., Muka, T., Van Meurs, J. B. J., Alferink, L. J. M., Franco, O. H. & 17 others, , Jan 1 2019, In : Diabetes. 68, 5, p. 1073-1083 11 p.Research output: Contribution to journal › Article
2
Scopus
citations
Association of cord blood methylation with neonatal leptin: An epigenome wide association study
Kadakia, R., Zheng, Y., Zhang, Z., Zhang, W., Josefson, J. L. & Hou, L., Jan 1 2019, In : PloS one. 14, 12, e0226555.Research output: Contribution to journal › Article
Open Access
Comparative validation of an epigenetic mortality risk score with three aging biomarkers for predicting mortality risks among older adult males
Gao, X., Colicino, E., Shen, J., Just, A. C., Nwanaji-Enwerem, J. C., Wang, C., Coull, B., Lin, X., Vokonas, P., Zheng, Y., Hou, L., Schwartz, J. & Baccarelli, A. A., Dec 1 2019, In : International journal of epidemiology. 48, 6, p. 1958-1971 14 p.Research output: Contribution to journal › Article
2
Scopus
citations
Correction: Accelerated DNA methylation age and the use of antihypertensive medication among older adults [Aging, (Albany NY), 10, (2018), (3210-3228)] doi: 10.18632/aging.10162
Gao, X., Colicino, E., Shen, J., Just, A. C., Nwanaji-Enwerem, J. C., Coull, B., Lin, X., Vokonas, P., Zheng, Y., Hou, L., Schwartz, J. & Baccarelli, A. A., May 15 2019, In : Aging. 11, 9, 1 p.Research output: Contribution to journal › Comment/debate