• 1041 Citations
20042019
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Personal profile

Education/Academic qualification

PhD, Kyoto University, Japan

… → 2007

Fingerprint Dive into the research topics where Yohhei Takahashi is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 17 Similar Profiles
Histones Medicine & Life Sciences
Ubiquinone Medicine & Life Sciences
Yeasts Medicine & Life Sciences
Methylation Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Disulfides Medicine & Life Sciences
Histone Code Medicine & Life Sciences

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Grants 2016 2019

Research Output 2004 2019

  • 1041 Citations
  • 21 Article
  • 1 Comment/debate
6 Citations (Scopus)

USP7 cooperates with NOTch1 to drive the oncogenic transcriptional program in T-cell leukemia

Jin, Q., Martinez, C. A., Arcipowski, K. M., Zhu, Y., Gutierrez-Diaz, B. T., Wang, K. K., Johnson, M. R., Volk, A. G., Wang, F., Wu, J., Grove, C., Wang, H., Sokirniy, I., Thomas, P. M., Goo, Y. A., Abshiru, N. A., Hijiya, N., Peirs, S., Vandamme, N., Berx, G. & 27 others, Goosens, S., Marshall, S. A., Rendleman, E. J., Takahashi, Y., Wang, L., Rawat, R., Bartom, E. T., Collings, C. K., Van Vlierberghe, P., Strikoudis, A., Kelly, S., Ueberheide, B., Mantis, C., Kandela, I., Bourquin, J. P., Bornhauser, B., Serafin, V., Bresolin, S., Paganin, M., Accordi, B., Basso, G., Kelleher, N. L., Weinstock, J., Kumar, S., Crispino, J. D., Shilatifard, A. & Ntziachristos, P., Jan 1 2019, In : Clinical Cancer Research. 25, 1, p. 222-239 18 p.

Research output: Contribution to journalArticle

Open Access
Ubiquitin-Specific Proteases
T-Cell Leukemia
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Leukemia
Chromatin
20 Citations (Scopus)

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy

Wang, L., Zhao, Z., Ozark, P. A., Fantini, D., Marshall, S. A., Rendleman, E. J., Cozzolino, K. A., Louis, N., He, X., Morgan, M. A., Takahashi, Y., Collings, C. K., Smith, E., Ntziachristos, P., Savas, J. N., Zou, L., Hashizume, R., Meeks, J. J. & Shilatifard, A., Jun 1 2018, In : Nature Medicine. 24, 6, p. 758-769 12 p.

Research output: Contribution to journalArticle

Epigenomics
Tumors
Methyltransferases
Histones
Mutation
2 Citations (Scopus)

Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation

Haddad, J. F., Yang, Y., Takahashi, Y., Joshi, M., Chaudhary, N., Woodfin, A. R., Benyoucef, A., Yeung, S., Brunzelle, J. S., Skiniotis, G., Brand, M., Shilatifard, A. & Couture, J. F., Dec 4 2018, In : Structure. 26, 12, p. 1594-1603.e4

Research output: Contribution to journalArticle

Personnel Selection
Epigenomics
Methylation
Chromatin
Enzymes
11 Citations (Scopus)

Structure and Conformational Dynamics of a COMPASS Histone H3K4 Methyltransferase Complex

Qu, Q., Takahashi, Y., Yang, Y., Hu, H., Zhang, Y., Brunzelle, J. S., Couture, J. F., Shilatifard, A. & Skiniotis, G., Aug 23 2018, In : Cell. 174, 5, p. 1117-1126.e12

Research output: Contribution to journalArticle

Methyltransferases
Histones
Cryoelectron Microscopy
Proteins
Methylation
27 Citations (Scopus)

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability

Rickels, R., Herz, H. M., Sze, C. C., Cao, K., Morgan, M. A., Collings, C. K., Gause, M., Takahashi, Y., Wang, L., Rendleman, E. J., Marshall, S. A., Krueger, A., Bartom, E. T., Piunti, A., Smith, E., Abshiru, N. A., Kelleher, N. L., Dorsett, D. & Shilatifard, A., Nov 1 2017, In : Nature Genetics. 49, 11, p. 1647-1653 7 p.

Research output: Contribution to journalArticle

Histones
Drosophila
Embryonic Structures
Alleles
Methyltransferases