• Source: Scopus
19952020

Research output per year

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Personal profile

Research Interests

The overarching goal of Wan laboratory is to define the molecular mechanisms of breast tumor initiation, progression, and metastasis, and to identify novel targets for therapeutic development. Particularly, the laboratory seeks to address how defects in the ubiquitin-proteasome system and other posttranslational modifiers such as protein methyltransferase and poly (ADP-ribose) polymerase would result in genomic instability, abnormal cell cycle, and aberrant signaling that predispose otherwise normal cells to become cancerous tumor cells or promote cancer metastasis. The research approaches in Wan laboratory include biochemical, cell biological, genetic, protein structural analyses as well as the use of breast cancer animal models and analyses of clinical specimens.

Training Experience

2003Postdoctoral Fellowship, Harvard University

Education/Academic qualification

PhD, Cornell University

… → 1997

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