Young Kwang Chae

  • 2000 Citations
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Personal profile

Research Interests

Personalized Cancer Therapy, Precision Medicine, Early Phase Clinical Trials, First-in-Human Study, Novel Combination Cancer Therapy, Targeted therapy, Immunotherapy, Biomarker Study, Novel Drug Development, Novel Drug Delivery System, Adaptive Clinical Trials Design, Cell Signaling Pathway, Immune Checkpoint Pathway

Training Experience

2011Residency, Albert Einstein Medical Center
2014Fellowship, University of Texas/MD Anderson Cancer Center

Education/Academic qualification

MBA, Johns Hopkins University

… → 2007

MPH, Johns Hopkins University

… → 2007

MD, Seoul National University

… → 2002

Research interests

  • Oncology

Fingerprint Dive into the research topics where Young Kwang Chae is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Neoplasms Medicine & Life Sciences
Non-Small Cell Lung Carcinoma Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Immunotherapy Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Hydroxymethylglutaryl-CoA Reductase Inhibitors Medicine & Life Sciences
Biomarkers Medicine & Life Sciences
Lung Neoplasms Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2013 2025

Research Output 2007 2019

4 Citations (Scopus)

Analysis of cell-free DNA from 32,989 advanced cancers reveals novel co-occurring activating RET alterations and oncogenic signaling pathway aberrations

Rich, T. A., Reckamp, K. L., Chae, Y. K., Doebele, R. C., Iams, W. T., Oh, M., Raymond, V. M., Lanman, R. B., Riess, J. W., Stinchcombe, T. E., Subbiah, V., Trevarthen, D. R., Fairclough, S., Yen, J. & Gautschi, O., Jan 1 2019, In : Clinical Cancer Research. 25, 19, p. 5832-5842 11 p.

Research output: Contribution to journalArticle

Open Access
Gene Fusion
Circulating Neoplastic Cells
Phase II Clinical Trials
8 Citations (Scopus)

A phase I dose-escalation study of veliparib combined with carboplatin and etoposide in patients with extensive-stage small cell lung cancer and other solid tumors

Atrafi, F., Groen, H. J. M., Byers, L. A., Garralda, E., Lolkema, M. P., Sangha, R. S., Viteri, S., Chae, Y. K., Ross Camidge, D., Gabrail, N. Y., Hu, B., Tian, T., Nuthalapati, S., Hoening, E., He, L., Komarnitsky, P. & Calles, A., Jan 15 2019, In : Clinical Cancer Research. 25, 2, p. 496-505 10 p.

Research output: Contribution to journalArticle

Open Access
Small Cell Lung Carcinoma
Disease Progression
1 Citation (Scopus)

Association of the prognostic model iSEND with PD-1/L1 monotherapy outcome in non-small-cell lung cancer

Park, W., Mezquita, L., Okabe, N., Chae, Y. K., Kwon, D., Saravia, D., Auclin, E., Planchard, D., Caramella, C., Ferrara, R., Agte, S., Oh, M., Mudad, R., Jahanzeb, M., Suzuki, H., Besse, B. & Lopes, G., Jan 1 2019, (Accepted/In press) In : British Journal of Cancer.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
7 Citations (Scopus)

Association of Tumor Mutational Burden With DNA Repair Mutations and Response to Anti–PD-1/PD-L1 Therapy in Non–Small-Cell Lung Cancer

Chae, Y. K., Davis, A. A., Raparia, K., Agte, S., Pan, A., Mohindra, N. A., Villaflor, V. M. & Giles, F., Mar 1 2019, In : Clinical Lung Cancer. 20, 2, p. 88-96.e6

Research output: Contribution to journalArticle

Tumor Burden
Non-Small Cell Lung Carcinoma
DNA Repair

Clinical and Immunological Implications of Frameshift Mutations in Lung Cancer

Chae, Y. K., Viveiros, P., Lopes, G., Sukhadia, B., Sheikh, M. M., Saravia, D., Florou, V., Sokol, E. S., Frampton, G. M., Chalmers, Z. R., Ali, S. M., Ross, J. S., Chang, S., Wang, S., Chiec, L., Rahbari, A., Mohindra, N., Villaflor, V., Shin, S. H., Oh, M. & 5 others, Anker, J., Park, L. C., Wang, V., Chuang, J. & Park, W., Oct 2019, In : Journal of Thoracic Oncology. 14, 10, p. 1807-1817 11 p.

Research output: Contribution to journalArticle

Frameshift Mutation
Lung Neoplasms
Tumor Burden
Renal Cell Carcinoma