Grants per year
Personal profile
Research Interests
Personalized Cancer Therapy, Precision Medicine, Early Phase Clinical Trials, First-in-Human Study, Novel Combination Cancer Therapy, Targeted therapy, Immunotherapy, Biomarker Study, Novel Drug Development, Novel Drug Delivery System, Adaptive Clinical Trials Design, Cell Signaling Pathway, Immune Checkpoint Pathway
Training Experience
| 2011 | Residency, Albert Einstein Medical Center |
| 2014 | Fellowship, University of Texas/MD Anderson Cancer Center |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MBA, Medical Management, Johns Hopkins University
… → 2007
MPH, Public Health, Johns Hopkins University
… → 2007
MD, Medicine, Seoul National University
… → 2002
Research interests keywords
- Oncology
Fingerprint
Dive into the research topics where Young Kwang Chae is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Prot #1454‐0001: A First‐in‐Human Phase I, Non‐Randomized, Open‐Label, Multicenter Dose Escalation Trial of BI 765049 and BI 765049 + Ezabenlimab (BI 754091) Administered by Repeated Intravenous Infusions in Patients with Malignant Solid Tumors Expressi
Chae, Y. K. (PD/PI)
SCRI Development Innovations, LLC, Boehringer Ingelheim Pharmaceuticals, Inc.
11/10/23 → 11/10/26
Project: Research project
-
The distinct role of cysteinyl leukotriene receptor for myeloid-derived suppressive cells
Zhang, B. (PD/PI), Zhang, B. (PD/PI), Chae, Y. K. (Co-Investigator), Chae, Y. K. (Co-Investigator), Fang, D. (Co-Investigator), Fang, D. (Co-Investigator), Sosman, J. A. (Co-Investigator), Sosman, J. A. (Co-Investigator), Zou, L. (Co-Investigator) & Zou, L. (Co-Investigator)
5/15/20 → 4/30/26
Project: Research project
-
Prot #M16-573: A Phase 1 First-in-Human Study with ABBV-155 Alone and in Combination with Taxane Therapy in Adults with Relapsed and/or Refractory Solid Tumors
Chae, Y. K. (PD/PI)
10/17/19 → 10/17/26
Project: Research project
-
Prot #ISA101b-HN-01-17: A Randomized, Double-blind, Placebo-Controlled, Phase 2 Study of Cemiplimab Versus the Combination of Cemiplimab With ISA101b in the Treatment of Subjects With HPV16-Positive Platin-Resistant Oropharyngeal Cancer (OPC)
Chae, Y. K. (PD/PI)
Syneos Health, Inc., ISA Therapeutics B.V.
4/22/19 → 4/22/25
Project: Research project
-
A Phase II Basket Trial of Dual Anti–CTLA-4 and Anti–PD-1 Blockade in Rare Tumors (DART SWOG 1609 Cohort 47) in Patients with Gestational Trophoblastic Neoplasia
Patel, S. P., Othus, M., Chae, Y. K., Dennis, M. J., Gordon, S., Mutch, D., Samlowski, W., Rusty Robinson, W. R., Sharon, E., Ryan, C., Lopez, G., Plets, M., Blanke, C. & Kurzrock, R., Jan 10 2024, In: Clinical Cancer Research. 30, 1, p. 33-38 6 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Correlation between tumor size change and outcome in a rare cancer immunotherapy basket trial
Othus, M., Patel, S. P., Chae, Y. K., Dietrich, E., Streicher, H., Sharon, E. & Kurzrock, R., May 1 2024, In: Journal of the National Cancer Institute. 116, 5, p. 673-680 8 p.Research output: Contribution to journal › Article › peer-review
-
Deep response to a combination of mTOR inhibitor temsirolimus and dual immunotherapy of nivolumab/ipilimumab in poorly differentiated thyroid carcinoma with PTEN mutation: a case report and literature review
Oh, Y., Park, J. H., Djunadi, T. A., Shah, Z., Chung, L. I. Y. & Chae, Y. K., 2024, In: Frontiers in Endocrinology. 15, 1304188.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Incidence of immunotherapy-related hyperprogressive disease (HPD) across HPD definitions and cancer types in observational studies: A systematic review and meta-analysis
Kim, M. J., Hong, S. P. D., Park, Y. & Chae, Y. K., Feb 2024, In: Cancer medicine. 13, 3, e6970.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Inflamed immune phenotype predicts favorable clinical outcomes of immune checkpoint inhibitor therapy across multiple cancer types
Shen, J., Choi, Y. L., Lee, T., Kim, H., Chae, Y. K., Dulken, B. W., Bogdan, S., Huang, M., Fisher, G. A., Park, S., Lee, S. H., Hwang, J. E., Chung, J. H., Kim, L., Song, H., Pereira, S., Shin, S., Lim, Y., Ahn, C. H. & Kim, S. & 10 others, , Feb 14 2024, In: Journal for immunotherapy of cancer. 12, 2, 2024;12:e008339.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations
Datasets
-
-
-
-
Exceptional response to chemotherapy followed by concurrent radiotherapy and immunotherapy in a male with primary retroperitoneal serous Adenocarcinoma: a case report and literature review
Chae, Y. K. (Creator), Saleem, N. (Creator), Roh, Y. (Contributor), Bilal, H. (Creator), Viveiros, P. (Creator), Sukhadia, B. (Contributor), Lin, X. (Contributor), Sheikh, M. M. (Creator) & Park, L. C. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.c.4601576, https://springernature.figshare.com/collections/Exceptional_response_to_chemotherapy_followed_by_concurrent_radiotherapy_and_immunotherapy_in_a_male_with_primary_retroperitoneal_serous_Adenocarcinoma_a_case_report_and_literature_review/4601576
Dataset
-
Supplementary Material for: Cushing’s Syndrome in Adenocarcinoma of Lung Responding to Osilodrostat
Heleno, C. T. (Contributor), Hong, S. P. D. (Contributor), Cho, H.-G. (Contributor), Kim, M. J. (Contributor), Park, Y. (Contributor) & Chae, Y. K. (Contributor), Karger Publishers, 2023
DOI: 10.6084/m9.figshare.22146836.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Cushing_s_Syndrome_in_Adenocarcinoma_of_Lung_Responding_to_Osilodrostat/22146836/1
Dataset