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Young Kwang Chae

  • 2348 Citations
20072020

Research output per year

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Personal profile

Research Interests

Personalized Cancer Therapy, Precision Medicine, Early Phase Clinical Trials, First-in-Human Study, Novel Combination Cancer Therapy, Targeted therapy, Immunotherapy, Biomarker Study, Novel Drug Development, Novel Drug Delivery System, Adaptive Clinical Trials Design, Cell Signaling Pathway, Immune Checkpoint Pathway

Training Experience

2011Residency, Albert Einstein Medical Center
2014Fellowship, University of Texas/MD Anderson Cancer Center

Education/Academic qualification

MBA, Johns Hopkins University

… → 2007

MPH, Johns Hopkins University

… → 2007

MD, Seoul National University

… → 2002

Research interests

  • Oncology

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Grants

The distinct role of cysteinyl leukotriene receptor for myeloid-derived suppressive cells

Chae, Y. K., Fang, D., Sosman, J. A., Zhang, B. & Zou, L.

National Cancer Institute

5/15/20 → 4/30/25

Project: Research project

    • Prot #M16-573: A Phase 1 First-in-Human Study with ABBV-155 Alone and in Combination with Taxane Therapy in Adults with Relapsed and/or Refractory Solid Tumors

    Chae, Y. K.

    AbbVie Inc.

    10/17/19 → 10/17/20

    Project: Research project

    Early Therapeutics and Rare Cancer Vice Chair Role

    Chae, Y. K.

    Oregon Health and Science University, National Cancer Institute

    3/1/19 → 2/28/25

    Project: Research project

    • Prot #D6070C00004: A Multiarm, Open-label, Multicenter, Phase 1b/2 Study to Evaluate Novel Combination Therapies in Subjects with Previously Treated Advanced EGFRm NSCLC

    Chae, Y. K.

    ICON Clinical Research, LLC, MedImmune, LLC

    12/3/18 → 12/3/21

    Project: Research project

    NU 17Z01 (Freenome) - Blood Biomarker Analysis in Patients with Solid Tumors or Lymphoma

    Chae, Y. K.

    Freenome Holdings, Inc.

    12/21/17 → 12/21/20

    Project: Research project

    Research Output

    A Phase II Basket Trial of Dual Anti–CTLA-4 and Anti–PD-1 Blockade in Rare Tumors (DART SWOG 1609) in Patients with Nonpancreatic Neuroendocrine Tumors

    Patel, S. P., Othus, M., Chae, Y. K., Giles, F. J., Hansel, D. E., Singh, P. P., Fontaine, A., Shah, M. H., Kasi, A., Baghdadi, T. A., Matrana, M., Gatalica, Z., Korn, W. M., Hayward, J., McLeod, C., Chen, H. X., Sharon, E., Mayerson, E., Ryan, C. W., Plets, M. & 2 others, Blanke, C. D. & Kurzrock, R., May 15 2020, In : Clinical Cancer Research. 26, 10, p. 2290-2296 7 p.

    Research output: Contribution to journal › Article

    Open Access
    • 4 Scopus citations

    Association of the prognostic model iSEND with PD-1/L1 monotherapy outcome in non-small-cell lung cancer

    Park, W., Mezquita, L., Okabe, N., Chae, Y. K., Kwon, D., Saravia, D., Auclin, E., Planchard, D., Caramella, C., Ferrara, R., Agte, S., Oh, M., Mudad, R., Jahanzeb, M., Suzuki, H., Besse, B. & Lopes, G., Feb 4 2020, In : British Journal of Cancer. 122, 3, p. 340-347 8 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1–2 trials

    trial investigators, Feb 2020, In : The Lancet Oncology. 21, 2, p. 271-282 12 p.

    Research output: Contribution to journal › Article

    • 24 Scopus citations

    Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1–2 trials

    Drilon, A., Siena, S., Dziadziuszko, R., Barlesi, F., Krebs, M. G., Shaw, A. T., de Braud, F., Rolfo, C., Ahn, M. J., Wolf, J., Seto, T., Cho, B. C., Patel, M. R., Chiu, C. H., John, T., Goto, K., Karapetis, C. S., Arkenau, H. T., Kim, S. W., Ohe, Y. & 16 others, Li, Y. C., Chae, Y. K., Chung, C. H., Otterson, G. A., Murakami, H., Lin, C. C., Tan, D. S. W., Prenen, H., Riehl, T., Chow-Maneval, E., Simmons, B., Cui, N., Johnson, A., Eng, S., Wilson, T. R. & Doebele, R. C., Feb 2020, In : The Lancet Oncology. 21, 2, p. 261-270 10 p.

    Research output: Contribution to journal › Article

    • 9 Scopus citations

    Ipilimumab and Nivolumab in Rare Tumors S1609: Neuroendocrine-Response

    S1609 Team, May 15 2020, In : Clinical cancer research : an official journal of the American Association for Cancer Research. 26, 10, 1 p.

    Research output: Contribution to journal › Letter