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Young Kwang Chae

  • 1433 Citations
20072021
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Personal profile

Research Interests

Personalized Cancer Therapy, Precision Medicine, Early Phase Clinical Trials, First-in-Human Study, Novel Combination Cancer Therapy, Targeted therapy, Immunotherapy, Biomarker Study, Novel Drug Development, Novel Drug Delivery System, Adaptive Clinical Trials Design, Cell Signaling Pathway, Immune Checkpoint Pathway

Training Experience

2011Residency, Albert Einstein Medical Center
2014Fellowship, University of Texas/MD Anderson Cancer Center

Education/Academic qualification

MBA, Johns Hopkins University

… → 2007

MPH, Johns Hopkins University

… → 2007

MD, Seoul National University

… → 2002

Keywords

  • Oncology

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Methylation Medicine & Life Sciences
Biomarkers Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2013 2021

Prot #D6070C00004: A Multiarm, Open-label, Multicenter, Phase 1b/2 Study to Evaluate Novel Combination Therapies in Subjects with Previously Treated Advanced EGFRm NSCLC

Chae, Y. K.

ICON Clinical Research, LLC, MedImmune, LLC

12/3/18 → 12/3/21

Project: Research project

NU 17Z01 (Freenome) - Blood Biomarker Analysis in Patients with Solid Tumors or Lymphoma

Chae, Y. K.

Freenome Holdings, Inc.

12/21/17 → 12/21/20

Project: Research project

NU 17Z01 - Blood Biomarker Analysis in Patients with Solid Tumors or Lymphoma

Chae, Y. K.

Biodesix, Inc.

12/14/17 → 12/14/20

Project: Research project

NU 17Z01 (Lexent Bio) - Blood Biomarker Analysis in Patients with Solid Tumors or Lymphoma

Chae, Y. K.

Lexent Bio, Inc.

12/14/17 → 12/14/20

Project: Research project

Early Therapeutics and Rare Cancer Vice Chair Role

Chae, Y. K.

Oregon Health & Science University , National Cancer Institute

9/1/17 → 2/28/19

Project: Research project

Research Personnel
Neoplasms
Therapeutics
Strategic Planning
Mentoring

Research Output 2007 2018

1 Citations

Anaplastic lymphoma kinase mutation (ALK F1174C) in small cell carcinoma of the prostate and molecular response to alectinib

Carneiro, B. A., Pamarthy, S., Shah, A. N., Sagar, V., Unno, K., Han, H. Y., Yang, X. J., Costa, R. B., Nagy, R. J., Lanman, R. B., Kuzel, T. M., Ross, J. S., Gay, L., Elvin, J. A., Ali, S. M., Cristofanilli, M., Chae, Y. K., Giles, F. J. & Abdulkadir, S. A., Jun 15 2018, In : Clinical Cancer Research. 24, 12, p. 2732-2739 8 p.

Research output: Contribution to journal › Article

Small Cell Carcinoma
Prostate
Mutation
Organoids
Prostatic Neoplasms

Association of Tumor Mutational Burden With DNA Repair Mutations and Response to Anti–PD-1/PD-L1 Therapy in Non–Small-Cell Lung Cancer

Chae, Y. K., Davis, A. A., Raparia, K., Agte, S., Pan, A., Mohindra, N. A., Villaflor, V. M. & Giles, F., Jan 1 2018, (Accepted/In press) In : Clinical Lung Cancer.

Research output: Contribution to journal › Article

CD274 Antigen
Tumor Burden
Non-Small Cell Lung Carcinoma
DNA Repair
Mutation
4 Citations

Cancer immunotherapy in a neglected population: The current use and future of T-cell-mediated checkpoint inhibitors in organ transplant patients

Chae, Y. K., Galvez, C., Anker, J. F., Iams, W. T. & Bhave, M., Feb 1 2018, In : Cancer Treatment Reviews. 63, p. 116-121 6 p.

Research output: Contribution to journal › Review article

Immunotherapy
T-Lymphocytes
Transplants
Allografts
Population
9 Citations

Current landscape and future of dual anti-CTLA4 and PD-1/PD-L1 blockade immunotherapy in cancer; lessons learned from clinical trials with melanoma and non-small cell lung cancer (NSCLC)

Chae, Y. K., Arya, A., Iams, W., Cruz, M. R., Chandra, S., Choi, J. & Giles, F., May 16 2018, In : Journal for ImmunoTherapy of Cancer. 6, 1, 39.

Research output: Contribution to journal › Review article

Non-Small Cell Lung Carcinoma
Immunotherapy
Melanoma
Clinical Trials
CTLA-4 Antigen

Deep and Durable Response with Combination CTLA-4 and PD-1 Blockade in Mismatch Repair (MMR)-proficient Endometrial Cancer

Oh, M. S. & Chae, Y. K., Jan 1 2018, (Accepted/In press) In : Journal of Immunotherapy.

Research output: Contribution to journal › Article

DNA Mismatch Repair
Endometrial Neoplasms
Immunotherapy
Ligands
Neoplasms