Grants per year
Personal profile
Research Interests
His research interests include machine learning, natural language processing, time series analysis, integrative genomic analysis and big data analytics, with a focus on medical and clinical applications. He is the Chief AI Scientist at Northwestern University Clinical and Translational Sciences Institute (NUCATS).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Electrical Engineering and Computer Science, PhD, MIT
… → 2015
Research interests keywords
- Autism Spectrum Disorders
- Bioinformatics
- Biomedical Ontologies
- Blood Cancer (leukemia and lymphomas)
- Computational Biology
- Critical Care
- Genomics
- Medical Informatics
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Collaborations and top research areas from the last five years
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Beating the odds: leveraging large language models to predict CCU readmission in patients with heart failure
Luo, Y. (PD/PI)
1/1/25 → 12/31/26
Project: Research project
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Natural Language Processing for Determining the Burden of Food Allergy among Children and Adults using Electronic Health Records
Bilaver, L. A. (PD/PI), Gupta, R. S. (Co-PD/PI), Eisenbarth, S. C. (Co-Investigator), French, D. D. (Co-Investigator), Luo, Y. (Co-Investigator), Patel, G. B. (Co-Investigator), Starren, J. (Co-Investigator) & Warren, C. M. (Co-Investigator)
9/3/24 → 8/31/25
Project: Research project
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Element B + Subcontracts
Becker, S. (PD/PI), D'Aquila, R. T. (PD/PI), Yancy, C. W. (PD/PI), Alshurafa, N. (Other), Ameer, G. A. (Other), Beidas, R. S. (Other), Blanco, I. (Other), Bradley, C. D. (Other), Brawley, C. (Other), Brown, O. E. (Other), Brown, C. H. (Other), Cameron, K. A. (Other), Carnethon, M. R. (Other), Cooper, L. A. D. (Other), Feinstein, M. J. (Other), Franklin, P. D. (Other), Helseth, S. A. (Other), Hill, V. B. (Other), Holmes, K. (Other), Kalhan, R. (Other), Khan, S. S. (Other), Kho, A. N. (Other), Li, D. H. (Other), Liebovitz, D. M. (Other), Luo, Y. (Other), Macapagal, K. (Other), O'Brien, M. J. (Other), Passman, R. S. (Other), Perreault, E. (Other), Peters, A. T. (Other), Pickens, C. I. (Other), Rasmussen-Torvik, L. J. (Other), Rivnay, J. (Other), Rosenberg, S. R. (Other), Schauer, J. M. (Other), Scott, K. (Other), Scott, E. A. (Other), Simon, M. A. (Other), Skolarus, L. E. (Other), Spring, B. (Other), Starren, J. (Other), Tandon, D. (Other), Walunas, T. L. (Other), Welty, L. J. (Other), Woitowich, N. C. (Other) & Wolf, M. (Other)
National Center for Advancing Translational Sciences
9/1/24 → 7/31/31
Project: Research project
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Building Informatics Tools for the Identification of Chronic Spontaneous Urticaria using Electronic Health Records
Bilaver, L. A. (PD/PI), Luo, Y. (Co-Investigator) & Mao, C. (Co-Investigator)
8/19/24 → 8/30/25
Project: Research project
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Machine learning to predict the development of ventilator-associated pneumonia
Luo, Y. (PD/PI), Wunderink, R. G. (PD/PI), Gao, C. A. (Other) & Singer, B. (Other)
American Thoracic Society, Inc.
7/1/24 → 7/1/25
Project: Research project
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A common longitudinal intensive care unit data format (CLIF) for critical illness research
Rojas, J. C., Lyons, P. G., Chhikara, K., Chaudhari, V., Bhavani, S. V., Nour, M., Buell, K. G., Smith, K. D., Gao, C. A., Amagai, S., Mao, C., Luo, Y., Barker, A. K., Nuppnau, M., Hermsen, M., Koyner, J. L., Beck, H., Baccile, R., Liao, Z. & Carey, K. A. & 8 others, , 2025, (Accepted/In press) In: Intensive Care Medicine. 160035.Research output: Contribution to journal › Article › peer-review
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A metabolic shift to the serine pathway induced by lipids fosters epigenetic reprogramming in nontransformed breast cells
Eduardo, M. B., Cottone, G., McCloskey, C. W., Liu, S., Palma, F. R., Zappia, M. P., Islam, A. B. M. M. K., Gao, P., Setya, J., Dennis, S., Gao, H., Zhang, Q., Xuei, X., Luo, Y., Locasale, J., Bonini, M., Khokha, R., Frolov, M. V., Benevolenskaya, E. V. & Chandel, N. S. & 2 others, , Mar 21 2025, In: Science Advances. 11, 12, eads9182.Research output: Contribution to journal › Article › peer-review
Open Access -
Correction to: A common longitudinal intensive care unit data format (CLIF) for critical illness research (Intensive Care Medicine, (2025), 10.1007/s00134-025-07848-7)
Rojas, J. C., Lyons, P. G., Chhikara, K., Chaudhari, V., Bhavani, S. V., Nour, M., Buell, K. G., Smith, K. D., Gao, C. A., Amagai, S., Mao, C., Luo, Y., Barker, A. K., Nuppnau, M., Hermsen, M., Koyner, J. L., Beck, H., Baccile, R., Liao, Z. & Carey, K. A. & 8 others, , 2025, (Accepted/In press) In: Intensive Care Medicine.Research output: Contribution to journal › Comment/debate › peer-review
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Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants
Regeneron Genetics Center‡, GHS-RGC DiscovEHR Collaboration§, Penn Medicine BioBank¶, Regeneron Genetics Center, GHS-RGC DiscovEHR Collaboration & Penn Medicine BioBank, Feb 7 2025, In: Science (New York, N.Y.). 387, 6734, p. eadp4753Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Leveraging large language models for academic conference organization
Luo, Y., Li, Y., Ogunyemi, O., Koski, E. & Himes, B. E., Dec 2025, In: npj Digital Medicine. 8, 1, 101.Research output: Contribution to journal › Comment/debate › peer-review
Open Access
Datasets
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Under-specification as the source of ambiguity and vagueness in narrative phenotype algorithm definitions
Yu, J. (Creator), Pacheco, J. A. (Creator), Ghosh, A. S. (Creator), Luo, Y. (Creator), Weng, C. (Creator), Shang, N. (Creator), Benoit, B. (Creator), Carrell, D. S. (Creator), Carroll, R. J. (Creator), Dikilitas, O. (Creator), Freimuth, R. R. (Creator), Gainer, V. S. (Creator), Hakonarson, H. (Creator), Hripcsak, G. (Creator), Kullo, I. J. (Creator), Mentch, F. (Creator), Murphy, S. N. (Creator), Peissig, P. L. (Creator), Ramirez, A. H. (Creator), Walton, N. (Creator), Wei, W.-Q. (Creator), Rasmussen, L. V. (Creator) & Pacheco, J. A. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.c.5816519, https://springernature.figshare.com/collections/Under-specification_as_the_source_of_ambiguity_and_vagueness_in_narrative_phenotype_algorithm_definitions/5816519
Dataset
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Using natural language processing and machine learning to identify breast cancer local recurrence
Zeng, Z. (Contributor), Espino, S. (Contributor), Roy, A. (Contributor), Li, X. (Contributor), Khan, S. A. (Creator), Clare, S. E. (Creator), Jiang, X. (Creator), Neapolitan, R. (Creator) & Luo, Y. (Creator), figshare, 2018
DOI: 10.6084/m9.figshare.c.4349627, https://springernature.figshare.com/collections/Using_natural_language_processing_and_machine_learning_to_identify_breast_cancer_local_recurrence/4349627
Dataset
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Additional file 1: of Using natural language processing and machine learning to identify breast cancer local recurrence
Zeng, Z. (Contributor), Espino, S. (Contributor), Roy, A. (Contributor), Li, X. (Contributor), Khan, S. A. (Creator), Clare, S. E. (Creator), Jiang, X. (Creator), Neapolitan, R. (Creator) & Luo, Y. (Creator), figshare, 2018
DOI: 10.6084/m9.figshare.7528163, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Using_natural_language_processing_and_machine_learning_to_identify_breast_cancer_local_recurrence/7528163
Dataset
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Datasets and metadata supporting the published article: Somatic Genetic Aberrations in Benign Breast Disease and the Risk of Subsequent Breast Cancer
Zeng, Z. (Contributor), Vo, A. (Creator), Li, X. (Contributor), Shidfar, A. (Creator), Saldana, P. (Creator), Blanco, L. (Creator), Xuei, X. (Contributor), Luo, Y. (Creator), Khan, S. A. (Creator) & Clare, S. E. (Creator), figshare, 2020
DOI: 10.6084/m9.figshare.12191793.v1, https://springernature.figshare.com/articles/Datasets_and_metadata_supporting_the_published_article_Somatic_Genetic_Aberrations_in_Benign_Breast_Disease_and_the_Risk_of_Subsequent_Breast_Cancer/12191793/1
Dataset
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Additional file 5 of Deep learning for cancer type classification and driver gene identification
Zeng, Z. (Creator), Mao, C. (Creator), Vo, A. (Creator), Li, X. (Creator), Nugent, J. O. (Creator), Khan, S. A. (Creator), Clare, S. E. (Creator) & Luo, Y. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.16864960, https://springernature.figshare.com/articles/dataset/Additional_file_5_of_Deep_learning_for_cancer_type_classification_and_driver_gene_identification/16864960
Dataset