Grants per year
Personal profile
Research Interests
The mission of our research is to understand the pain experience in individuals with systemic rheumatic conditions, such as rheumatoid arthritis (RA), and to identify the relationship between these experiences and pain pathways. This research is important because it paves the way for the development of effective pain prevention and management strategies to improve the well-being of our patients.
Training Experience
2006 | Residency, Barnes Jewish Hospital |
2009 | Fellowship, Brigham & Women's Hospital |
Education/Academic qualification
MMSc, Medical Science, Harvard Medical School
… → 2009
MD, Medicine, University of Michigan
… → 2003
Research interests keywords
- Arthritis - Rheumatoid
- Osteoarthritis
- Pain
- Rheumatology
- Sleep and Sleep Disorders
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Collaborations and top research areas from the last five years
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Pain and synovial pathotypes in AMP AIM (AWD00005387)
Ruderman, E. M. (PD/PI) & Lee, Y. C. (Co-Investigator)
University of Rochester, National Institute of Arthritis and Musculoskeletal and Skin Diseases
9/18/23 → 12/31/26
Project: Research project
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Mentored Patient-Oriented Research of Novel Mechanisms Linking Pain, Sleep-Wake Patterns, and Autonomic Activity in Rheumatic Diseases
Lee, Y. C. (PD/PI), Lee, Y. C. (PD/PI), Grimaldi, D. (Other), Grimaldi, D. (Other), Reid, K. J. (Other) & Reid, K. J. (Other)
National Institute of Arthritis and Musculoskeletal and Skin Diseases
2/24/23 → 1/31/28
Project: Research project
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Core Center for Clinical Research at Northwestern University
Sharma, L. (PD/PI), Sharma, L. (PD/PI), Bass, M. (Co-Investigator), Brown, C. H. (Co-Investigator), Chmiel, J. S. (Co-Investigator), Cuda, C. M. (Co-Investigator), Franklin, P. D. (Co-Investigator), Ghomrawi, H. (Co-Investigator), Holmes, K. (Co-Investigator), Holmes, K. (Co-Investigator), Kershaw, K. N. (Co-Investigator), Kershaw, K. N. (Co-Investigator), Lattie, E. G. (Co-Investigator), Muhammad, L. N. (Co-Investigator), Pope, R. M. (Co-Investigator), Pope, R. M. (Co-Investigator), Spring, B. (Co-Investigator), Tandon, D. (Co-Investigator), Van Horn, L. (Co-Investigator), Wehbe, F. (Co-Investigator), Winter, D. R. (Co-Investigator), Chang, R. W. (Other), Lee, Y. C. (Other), Lee, J. (Other), Lee, Y. C. (Other), Ramsey-Goldman, R. (Other) & Rothrock, N. (Other)
National Institute of Arthritis and Musculoskeletal and Skin Diseases
9/21/22 → 8/31/27
Project: Research project
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Transcriptional Profiles of Circulating Monocytes and their Association with Pain Centralization and DMARD response in Rheumatoid Arthritis
Lee, Y. C. (PD/PI), Lee, Y. C. (PD/PI), Lee, Y. C. (PD/PI), Cuda, C. M. (Co-Investigator), Cuda, C. M. (Co-Investigator), Cuda, C. M. (Co-Investigator), Muhammad, L. N. (Co-Investigator), Muhammad, L. N. (Co-Investigator), Muhammad, L. N. (Co-Investigator), Winter, D. R. (Co-Investigator), Winter, D. R. (Co-Investigator) & Winter, D. R. (Co-Investigator)
Rheumatology Research Foundation
7/1/22 → 6/30/25
Project: Research project
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Macrophage Heterogeneity in Rheumatoid Arthritis
Perlman, H. R. (PD/PI), Winter, D. R. (PD/PI), Cuda, C. M. (Co-Investigator), Lee, Y. C. (Co-Investigator), Mandelin, A. M. (Co-Investigator) & Muhammad, L. N. (Co-Investigator)
National Institute of Arthritis and Musculoskeletal and Skin Diseases
4/15/22 → 2/28/27
Project: Research project
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Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue
Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium, Dec 2024, In: Nature communications. 15, 1, 7503.Research output: Contribution to journal › Article › peer-review
Open Access -
Characterization of sleep disturbance in established rheumatoid arthritis patients: exploring the relationship with central nervous system pain regulation
Aydemir, B., Muhammad, L. N., Song, J., Reid, K. J., Grimaldi, D., Isaacs, A., Carns, M., Dennis-Aren, K., Dunlop, D. D., Chang, R. W., Zee, P. C. & Lee, Y. C., Dec 2024, In: BMC Rheumatology. 8, 1, 33.Research output: Contribution to journal › Article › peer-review
Open Access -
Characterizing Nonarticular Pain at Early Rheumatoid Arthritis Diagnosis: Evolution Over the First Year of Treatment and Impact on Remission in a Prospective Real-World Early Rheumatoid Arthritis Cohort
the Canadian Early Arthritis Cohort Investigators, 2024, (Accepted/In press) In: Arthritis and Rheumatology.Research output: Contribution to journal › Article › peer-review
Open Access -
Designing target trials using electronic health records: A case study of second-line disease-modifying anti-rheumatic drugs and cardiovascular disease outcomes in patients with rheumatoid arthritis
Rivera, A. S., Pierce, J. B., Sinha, A., Pawlowski, A. E., Lloyd-Jones, D. M., Lee, Y. C., Feinstein, M. J. & Petito, L. C., Jun 2024, In: PloS one. 19, 6 June, e0305467.Research output: Contribution to journal › Article › peer-review
Open Access -
Experiences of telehealth during and after the COVID-19 pandemic and preferences for future care of people with systemic sclerosis: a cross-sectional study
Scleroderma Patient-centered Intervention Network (SPIN) COVID-19 Patient Advisory Team, on behalf of the SPIN Investigators, Oct 2024, In: The Lancet Rheumatology. 6, 10, p. e660-e663Research output: Contribution to journal › Comment/debate › peer-review