Grants per year
Personal profile
Research Interests
Primary research interest involves identifying key molecule pathways (e.g. TLRs signaling pathways) leading to allograft rejection following organ transplantation using small animal transplant models.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, Medicine, Tongji Medical University, China
… → 1983
Research interests keywords
- Immune Regulation
- Immunology
- Inflammation
- Transplantation
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Collaborations and top research areas from the last five years
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Computational Drug Repositioning for Antibody Mediated Renal Allograft Rejection
Zhang, Z. J. (PD/PI)
University of California, San Francisco, National Institute of Allergy and Infectious Diseases
2/1/25 → 4/30/29
Project: Research project
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Mitigating IRI-induced CMV reactivation by targeting endothelial stress responses
Nadig, S. N. (PD/PI), Zhang, Z. J. (PD/PI), Burke, J. A. (Co-Investigator), Jaishankar, D. (Co-Investigator), Kanwar, Y. S. (Co-Investigator), Schipma, M. J. (Co-Investigator), Scott, E. A. (Co-Investigator) & Zhao, L. (Other)
National Institute of Allergy and Infectious Diseases
1/1/25 → 12/31/25
Project: Research project
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Sites-Specific Nanofiber-Coated Regulatory T Cells for the Induction of Tolerance in Vascularized Composite Allotransplants
Zhang, Z. J. (PD/PI), Zhang, Z. J. (PD/PI), Zhang, Z. J. (PD/PI), Zhang, Z. J. (PD/PI), Stupp, S. (Co-Investigator), Stupp, S. (Co-Investigator), Stupp, S. (Co-Investigator), Stupp, S. (Co-Investigator), Zhao, L. (Co-Investigator), Zhao, L. (Co-Investigator), Zhao, L. (Co-Investigator) & Zhao, L. (Co-Investigator)
U.S. Army Medical Research and Materiel Command
9/15/21 → 9/14/25
Project: Research project
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Allograft Inflammatory Factor-1 and Immune Tolerance
Zhang, Z. J. (PD/PI)
Albert Einstein College of Medicine, National Institute of Allergy and Infectious Diseases
6/1/23 → 5/31/24
Project: Research project
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Targeting Ischemia/Reperfusion Stress to Inhibit Cytomegalovirus Reactivation After Lung Transplant
Zhang, Z. J. (PD/PI), Zhang, Z. J. (PD/PI), Scott, E. A. (Co-Investigator), Scott, E. A. (Co-Investigator), Thorp, E. B. (Co-Investigator) & Thorp, E. B. (Co-Investigator)
National Institute of Allergy and Infectious Diseases
2/25/22 → 1/31/25
Project: Research project
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Altered kidney distribution and loss of ACE2 into the urine in acute kidney injury
Shirazi, M., Cianfarini, C., Ismail, A., Wysocki, J., Wang, J. J., Ye, M., Zhang, Z. J. & Batlle, D., Sep 2024, In: American Journal of Physiology - Renal Physiology. 327, 3, p. F412-F425Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Blocking antibodies against integrin-α3, -αM, and -αMβ2 de-differentiate myofibroblasts, and improve lung fibrosis and kidney fibrosis
White, M. J. V., Ozkan, M., Gomez-Medellin, J. E., Rączy, M. M., Koss, K. M., Solanki, A., Zhang, Z. J., Alpar, A. T., Naved, B. A., Wertheim, J. & Hubbell, J. A., Dec 2024, In: Scientific reports. 14, 1, 21623.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Hypoxia inducible factor 2α promotes tolerogenic macrophage development during cardiac transplantation through transcriptional regulation of colony stimulating factor 1 receptor
DeBerge, M., Schroth, S., Du, F., Yeap, X. Y., Wang, J. J., Zhang, Z. J., Ansari, M. J., Scott, E. A. & Thorp, E. B., Jun 1 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 26, e2319623121.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Toward discovering a novel family of peptides targeting neuroinflammatory states of brain microglia and astrocytes
Koss, K. M., Son, T., Li, C., Hao, Y., Cao, J., Churchward, M. A., Zhang, Z. J., Wertheim, J. A., Derda, R. & Todd, K. G., Oct 2024, In: Journal of neurochemistry. 168, 10, p. 3386-3414 29 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Beyond UPR: cell-specific roles of ER stress sensor IRE1α in kidney ischemic injury and transplant rejection
Qiu, L., Zheng, X., Jaishankar, D., Green, R., Fang, D., Nadig, S. & Zhang, Z. J., Sep 2023, In: Kidney international. 104, 3, p. 463-469 7 p.Research output: Contribution to journal › Short survey › peer-review
Open Access7 Scopus citations