Grants per year
Personal profile
Research Interests
protein folding, misfolding, aggregation, amyloidogenesis, prion, yeast genetics and protein misfolding disorders.
Training Experience
2009 | Postdoctoral Fellowship, Northwestern University |
Education/Academic qualification
Molecular Biology, PhD, Heidelberg University
… → 2002
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Collaborations and top research areas from the last five years
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Understanding prion-mediated transcriptional modifications and cellular phenotypes: insights into the role of Swi1 prion and prion-like behaviors of BAF proteins
Du, Z. (PD/PI), Bartom, E. T. (Co-Investigator) & Li, L. (Co-Investigator)
National Institute of General Medical Sciences
8/1/24 → 5/31/28
Project: Research project
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Prion-mediated protein aggregation/co-aggregation and cellular consequence
Du, Z. (PD/PI), Li, L. (Co-Investigator) & Savas, J. N. (Co-Investigator)
National Institute of General Medical Sciences
8/1/18 → 7/31/24
Project: Research project
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High Throughput Screening for Small-molecules Facilitating Prion Study
Li, L. (PD/PI), Du, Z. (Co-Investigator), Ferreira, A. B. (Co-Investigator) & Luan, C.-H. (Other)
National Institute of General Medical Sciences
7/1/14 → 6/30/18
Project: Research project
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Identifying Endogenous Cellular Proteins Destabilizing the Propagation of Swi1 Prion upon Overproduction
Du, Z., Cho, B. & Li, L., Jul 2022, In: Viruses. 14, 7, 1366.Research output: Contribution to journal › Article › peer-review
Open Access -
Defining key residues of the Swi1 prion domain in prion formation and maintenance
Goncharoff, D. K., Cabral, R., Applebey, S. V., Pagadala, M., Du, Z. & Li, L., Jun 2021, In: Molecular and cellular biology. 41, 7, e00044-21.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
A distinct class of plant and animal viral proteins that disrupt mitosis by directly interrupting the mitotic entry switch Wee1-Cdc25-Cdk1
Jin, H., Du, Z., Zhang, Y., Antal, J., Xia, Z., Wang, Y., Gao, Y., Zhao, X., Han, X., Cheng, Y., Shen, Q., Zhang, K., Elder, R. E., Benko, Z., Fenyvuesvolgyi, C., Li, G., Rebello, D., Li, J., Bao, S. & Zhao, R. Y. & 1 others, , May 2020, In: Science Advances. 6, 20, eaba3418.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Elucidating the regulatory mechanism of Swi1 prion in global transcription and stress responses
Du, Z., Regan, J., Bartom, E., Wu, W. S., Zhang, L., Goncharoff, D. K. & Li, L., Dec 2020, In: Scientific reports. 10, 1, 21838.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Identifying Anti-prion Chemical Compounds Using a Newly Established Yeast High-Throughput Screening System
Du, Z., Valtierra, S., Cardona, L. R., Dunne, S. F., Luan, C. H. & Li, L., Dec 19 2019, In: Cell Chemical Biology. 26, 12, p. 1664-1680.e4Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations