Grants per year
Personal profile
Training Experience
| 2004 | Postdoctoral Fellowship, Northwestern University Feinberg School of Medicine |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Neuroscience, University of Southern California
… → 2001
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Dive into the research topics where Zhong Xie is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Bifunctional intrabody targeting intracellular alpha-synuclein
Surmeier Jr, D. J. (PD/PI), Surmeier Jr, D. J. (PD/PI), Surmeier Jr, D. J. (PD/PI), Xie, Z. (Other), Xie, Z. (Other) & Xie, Z. (Other)
Michael J. Fox Foundation for Parkinson's Research
2/1/22 → 8/1/25
Project: Research project
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Molecular and Cellular Mechanisms of Parkinson's Disease
Surmeier Jr, D. J. (PD/PI), Surmeier Jr, D. J. (PD/PI), Surmeier Jr, D. J. (PD/PI), Guzman-Lucero, J. N. (Other), Guzman-Lucero, J. N. (Other), Guzman-Lucero, J. N. (Other), Ilijic, E. (Other), Ilijic, E. (Other), Ilijic, E. (Other), Shen, W. (Other), Shen, W. (Other), Shen, W. (Other), Wokosin, D. L. (Other), Wokosin, D. L. (Other), Wokosin, D. L. (Other), Xie, Z. (Other), Xie, Z. (Other), Xie, Z. (Other), Zampese, E. (Other) & Zampese, E. (Other)
11/1/21 → 10/31/25
Project: Research project
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Lead Identification of Novel Negative Allosteric Modulators of Cav1.3 L-Type Calcium Channels as a Disease Modifying Therapy for PD
Surmeier Jr, D. J. (PD/PI), Silverman, R. B. (Co-Investigator), Vanoye, C. G. (Co-Investigator) & Xie, Z. (Other)
Michael J. Fox Foundation for Parkinson's Research
8/1/21 → 7/31/23
Project: Research project
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Neural Adaptations in Huntington's Disease
Surmeier Jr, D. J. (PD/PI), Surmeier Jr, D. J. (PD/PI), Bevan, M. D. (Co-Investigator), Bevan, M. D. (Co-Investigator), Atherton, J. F. (Other), Atherton, J. F. (Other), Callahan, J. W. (Other), Callahan, J. W. (Other), Day, M. (Other), Day, M. (Other), Kondapalli, J. (Other), Kondapalli, J. (Other), Pancani, T. (Other), Pancani, T. (Other), Wokosin, D. L. (Other), Wokosin, D. L. (Other), Xie, Z. (Other) & Xie, Z. (Other)
4/1/18 → 3/31/25
Project: Research project
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Convergent amelioration of mitochondrial oxidant stress in substantia nigra dopamine neurons by isradipine and rasagiline
Surmeier Jr, D. J. (PD/PI) & Xie, Z. (Other)
Michael J. Fox Foundation for Parkinson's Research
9/1/15 → 8/31/16
Project: Research project
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Ca2+-dependent phosphodiesterase 1 regulates the plasticity of striatal spiny projection neuron glutamatergic synapses
Zhai, S., Otsuka, S., Xu, J., Clarke, V. R. J., Tkatch, T., Wokosin, D., Xie, Z., Tanimura, A., Agarwal, H. K., Ellis-Davies, G. C. R., Contractor, A. & Surmeier, D. J., Aug 27 2024, In: Cell reports. 43, 8, 114540.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
α-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinson’s disease
Geibl, F. F., Henrich, M. T., Xie, Z., Zampese, E., Ueda, J., Tkatch, T., Wokosin, D. L., Nasiri, E., Grotmann, C. A., Dawson, V. L., Dawson, T. M., Chandel, N. S., Oertel, W. H. & Surmeier, D. J., Dec 2024, In: Molecular neurodegeneration. 19, 1, 69.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Cholinergic deficits selectively boost cortical intratelencephalic control of striatum in male Huntington’s disease model mice
Pancani, T., Day, M., Tkatch, T., Wokosin, D. L., González-Rodríguez, P., Kondapalli, J., Xie, Z., Chen, Y., Beaumont, V. & Surmeier Jr, D. J., Dec 2023, In: Nature communications. 14, 1, 1398.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Parkinson's disease-linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons
Song, P., Peng, W., Sauve, V., Fakih, R., Xie, Z., Ysselstein, D., Krainc, T., Wong, Y. C., Mencacci, N. E., Savas, J. N., Surmeier, D. J., Gehring, K. & Krainc, D., Dec 6 2023, In: Neuron. 111, 23, p. 3775-3788.e7Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
Palladium-Catalyzed α-Arylation of Cyclic β-Dicarbonyl Compounds for the Synthesis of CaV1.3 Inhibitors
Yun, J., Jeong, D., Xie, Z., Lee, S., Kim, J., Surmeier, D. J., Silverman, R. B. & Kang, S., Apr 26 2022, In: ACS Omega. 7, 16, p. 14252-14263 12 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations
Datasets
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α-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinson’s disease
Chandel, N. S. (Creator), Grotmann, C. A. (Creator), Wokosin, D. L. (Creator), Xie, Z. (Creator), Nasiri, E. (Creator), Öertel, W. H. (Contributor) & Dawson, V. L. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.c.7485396.v1, https://springernature.figshare.com/collections/_-Synuclein_pathology_disrupts_mitochondrial_function_in_dopaminergic_and_cholinergic_neurons_at-risk_in_Parkinson_s_disease/7485396/1
Dataset