Zhuan Zhou

  • 1376 Citations
20042022

Research output per year

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Research Output

  • 1376 Citations
  • 37 Article
  • 3 Review article
  • 1 Chapter
  • 1 Comment/debate
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Article
2020

Regulation of KLF4 by posttranslational modification circuitry in endocrine resistance

Zhou, Z., Song, X., Chi, J. J., Gius, D. R., Huang, Y., Cristofanilli, M. & Wan, Y., Jun 2020, In : Cellular Signalling. 70, 109574.

Research output: Contribution to journalArticle

2019

A novel small-molecule antagonizes PRMT5-mediated KLF4 methylation for targeted therapy

Zhou, Z., Feng, Z., Hu, D., Yang, P., Gur, M., Bahar, I., Cristofanilli, M., Gradishar, W. J., Xie, X. Q. & Wan, Y., Jun 2019, In : EBioMedicine. 44, p. 98-111 14 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

A novel strategy to block mitotic progression for targeted therapy

Chi, J. J., Li, H., Zhou, Z., Izquierdo-Ferrer, J., Xue, Y., Wavelet, C. M., Schiltz, G. E., Zhang, B., Cristofanilli, M., Lu, X., Bahar, I. & Wan, Y., Nov 2019, In : EBioMedicine. 49, p. 40-54 15 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

ATXN3 promotes breast cancer metastasis by deubiquitinating KLF4

Zou, H., Chen, H., Zhou, Z., Wan, Y. & Liu, Z., Dec 28 2019, In : Cancer Letters. 467, p. 19-28 10 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

An ADAM12 and FAK positive feedback loop amplifies the interaction signal of tumor cells with extracellular matrix to promote esophageal cancer metastasis

Luo, M. L., Zhou, Z., Sun, L., Yu, L., Sun, L., Liu, J., Yang, Z., Ran, Y., Yao, Y. & Hu, H., May 28 2018, In : Cancer Letters. 422, p. 118-128 11 p.

Research output: Contribution to journalArticle

6 Scopus citations
2017

Regulation of XIAP Turnover Reveals a Role for USP11 in Promotion of Tumorigenesis

Zhou, Z., Luo, A., Shrivastava, I., He, M., Huang, Y., Bahar, I., Liu, Z. & Wan, Y., Feb 1 2017, In : EBioMedicine. 15, p. 48-61 14 p.

Research output: Contribution to journalArticle

18 Scopus citations
2016

Insights into APC/C: From cellular function to diseases and therapeutics

Zhou, Z., He, M., Shah, A. A. & Wan, Y., Jul 13 2016, In : Cell Division. 11, 1, 9.

Research output: Contribution to journalArticle

38 Scopus citations

Signal-oriented pathway analyses reveal a signaling complex as a synthetic lethal target for p53 mutations

Lu, S., Cai, C., Yan, G., Zhou, Z., Wan, Y., Chen, V., Chen, L., Cooper, G. F., Obeid, L. M., Hannun, Y. A., Lee, A. V. & Lu, X., Dec 1 2016, In : Cancer Research. 76, 23, p. 6785-6794 10 p.

Research output: Contribution to journalArticle

2 Scopus citations
2015

Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis

Hu, D., Gur, M., Zhou, Z., Gamper, A., Hung, M. C., Fujita, N., Lan, L., Bahar, I. & Wan, Y., Sep 30 2015, In : Nature communications. 6, 8419.

Research output: Contribution to journalArticle

44 Scopus citations
2013

Hyperthermia enhances mapatumumab-induced apoptotic death through ubiquitin-mediated degradation of cellular FLIP(long) in human colon cancer cells

Song, X., Kim, S. Y., Zhou, Z., Lagasse, E., Kwon, Y. T. & Lee, Y. J., Apr 2013, In : Cell Death and Disease. 4, 4, e577.

Research output: Contribution to journalArticle

18 Scopus citations

Regulation of rad17 protein turnover unveils an impact of rad17-APC cascade in breast carcinogenesis and treatment

Zhou, Z., Jing, C., Zhang, L., Takeo, F., Kim, H., Huang, Y., Liu, Z. & Wan, Y., Jun 21 2013, In : Journal of Biological Chemistry. 288, 25, p. 18134-18145 12 p.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Novel insight into KLF4 proteolytic regulation in estrogen receptor signaling and breast carcinogenesis

Hu, D., Zhou, Z., Davidson, N. E., Huang, Y. & Wan, Y., Apr 20 2012, In : Journal of Biological Chemistry. 287, 17, p. 13584-13597 14 p.

Research output: Contribution to journalArticle

20 Scopus citations
2011

An novel role of sphingosine kinase-1 (SPHK1) in the invasion and metastasis of esophageal carcinoma

Pan, J., Tao, Y. F., Zhou, Z., Cao, B. R., Wu, S. Y., Zhang, Y. L., Hu, S. Y., Zhao, W. L., Wang, J., Lou, G. L., Li, Z., Feng, X. & Ni, J., Sep 22 2011, In : Journal of Translational Medicine. 9, 1, 157.

Research output: Contribution to journalArticle

50 Scopus citations

ATP synthase ecto-α-subunit: A novel therapeutic target for breast cancer

Pan, J., Sun, L. C., Tao, Y. F., Zhou, Z., Du, X. L., Peng, L., Feng, X., Wang, J., Li, Y. P., Liu, L., Wu, S. Y., Zhang, Y. L., Hu, S. Y., Zhao, W. L., Zhu, X. M., Lou, G. L. & Ni, J., Dec 8 2011, In : Journal of Translational Medicine. 9, 1, 211.

Research output: Contribution to journalArticle

25 Scopus citations

MMP28 (epilysin) as a novel promoter of invasion and metastasis in gastric cancer

Jian, P., Yanfang, T., Zhuan, Z., Jian, W., Xueming, Z. & Jian, N., May 26 2011, In : BMC cancer. 11, 200.

Research output: Contribution to journalArticle

23 Scopus citations

P-cadherin promotes liver metastasis and is associated with poor prognosis in colon cancer

Sun, L., Hu, H., Peng, L., Zhou, Z., Zhao, X., Pan, J., Sun, L., Yang, Z. & Ran, Y., Jul 1 2011, In : American Journal of Pathology. 179, 1, p. 380-390 11 p.

Research output: Contribution to journalArticle

46 Scopus citations

Retinoic acid induces HL-60 cell differentiation via the upregulation of miR-663

Jian, P., Li, Z. W., Fang, T. Y., Jian, W., Zhuan, Z., Mei, L. X., Yan, W. S. & Jian, N., May 23 2011, In : Journal of Hematology and Oncology. 4, 20.

Research output: Contribution to journalArticle

59 Scopus citations
2010

Tumor-suppressive mir-663 gene induces mitotic catastrophe growth arrest in human gastric cancer cells

Pan, J., Hu, H., Zhou, Z., Sun, L., Peng, L., Yu, L., Sun, L., Liu, J., Yang, Z. & Ran, Y., Jan 1 2010, In : Oncology reports. 24, 1, p. 105-112 8 p.

Research output: Contribution to journalArticle

84 Scopus citations
2009

A novel role for tissue factor pathway inhibitor-2 in the therapy of human esophageal carcinoma

Ran, Y., Pan, J., Hu, H., Zhou, Z., Sun, L., Peng, L., Yu, L., Sun, L., Liu, J. & Yang, Z., Jan 1 2009, In : Human Gene Therapy. 20, 1, p. 41-49 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

Antibody library-based tumor endothelial cells surface proteomic functional screen reveals migration-stimulating factor as an anti-angiogenic target

Hu, H., Ran, Y., Zhang, Y., Zhou, Z., Harris, S. J., Yu, L., Sun, L., Pan, J., Liu, J., Lou, J. & Yang, Z., Apr 1 2009, In : Molecular and Cellular Proteomics. 8, 4, p. 816-826 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway

Peng, L., Ran, Y. L., Hu, H., Yu, L., Liu, Q., Zhou, Z., Sun, Y. M., Sun, L. C., Pan, J., Sun, L. X., Zhao, P. & Yang, Z. H., Oct 20 2009, In : Carcinogenesis. 30, 10, p. 1660-1669 10 p.

Research output: Contribution to journalArticle

119 Scopus citations

Tumor cell-microenvironment interaction models coupled with clinical validation reveal CCL2 and SNCG as two predictors of colorectal cancer hepatic metastasis

Hu, H., Sun, L., Guo, C., Liu, Q., Zhou, Z., Peng, L., Pan, J., Yu, L., Lou, J., Yang, Z., Zhao, P. & Ran, Y., Sep 1 2009, In : Clinical Cancer Research. 15, 17, p. 5485-5493 9 p.

Research output: Contribution to journalArticle

56 Scopus citations
2008

Derlin-1 Is overexpressed on the tumor cell surface and enables antibody-mediated tumor targeting therapy

Ran, Y., Hu, H., Hu, D., Zhou, Z., Sun, Y., Yu, L., Sun, L., Pan, J., Liu, J., Liu, T. & Yang, Z., Oct 15 2008, In : Clinical Cancer Research. 14, 20, p. 6538-6545 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Effect of microRNA-10a on migration and invasion of gastric cancer cell line BGC823

Peng, L., Pan, J., Hu, H., Sun, L. C., Zhou, Z., Ran, Y. L. & Yang, Z. H., Oct 1 2008, In : Chinese Journal of Cancer Biotherapy. 15, 5, p. 417-421 5 p.

Research output: Contribution to journalArticle

Overexpression of cyclin B1 in human esophageal squamous cell carcinoma cells induces tumor cell invasive growth and metastasis

Song, Y., Zhao, C., Dong, L., Fu, M., Xue, L., Huang, Z., Tong, T., Zhou, Z., Chen, A., Yang, Z., Lu, N. & Zhan, Q., Feb 1 2008, In : Carcinogenesis. 29, 2, p. 307-315 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

Preperation and identification of HER2-targeting monoclonal antibodies suppressing gastric carcinoma cells

Sun, L. X., Ran, Y. L., Hu, H., Yu, L., Zhou, Z., Zhao, X. L. & Yang, Z. H., Feb 1 2008, In : Chinese Journal of Cancer Biotherapy. 15, 1, p. 14-19 6 p.

Research output: Contribution to journalArticle

Profiling tumor-associated autoantibodies for the detection of colon cancer

Ran, Y., Hu, H., Zhou, Z., Yu, L., Sun, L., Pan, J., Liu, J. & Yang, Z., May 1 2008, In : Clinical Cancer Research. 14, 9, p. 2696-2700 5 p.

Research output: Contribution to journalArticle

44 Scopus citations

TM4SF3 promotes esophageal carcinoma metastasis via upregulating ADAM12m expression

Zhou, Z., Ran, Y. L., Hu, H., Pan, J., Li, Z. F., Chen, L. Z., Sun, L. C., Peng, L., Zhao, X. L., Yu, L., Sun, L. X. & Yang, Z. H., Sep 1 2008, In : Clinical and Experimental Metastasis. 25, 5, p. 537-548 12 p.

Research output: Contribution to journalArticle

46 Scopus citations
2007

Expression of annexin I in human pancreatic cancer and the influence of its down-regulation on biology of this cancer

Liu, Q., Wang, C. F., Zhou, Z., Hu, H., Zhao, D. B., Ni, X. G., Bai, X. F., Gao, J. D., Tian, Y. T. & Zhao, P., Oct 2007, In : Zhonghua zhong liu za zhi [Chinese journal of oncology]. 29, 10, p. 738-741 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Human esophageal cancer endothelial cells increase tumor growth by incorporating with mouse endothelium

Hu, H., Zhang, Y., Ran, Y., Zhou, Z., Yu, L., Lou, J. & Yang, Z., Jul 8 2007, In : Cancer Letters. 252, 1, p. 123-130 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Preparation of functional antibodies targeting tumor endothelia for the treatment of hepatic carcinoma

Hu, H., Ran, Y. L., Yu, L., Zhou, Z., Lou, J. N. & Yang, Z. H., May 2007, In : Ai zheng = Aizheng = Chinese journal of cancer. 26, 5, p. 453-457 5 p.

Research output: Contribution to journalArticle

2006

Identification of derlin-1 as a novel growth factor-responsive endothelial antigen by suppression subtractive hybridization

Ran, Y., Jiang, Y., Zhong, X., Zhou, Z., Liu, H., Hu, H., Lou, J. N. & Yang, Z., Oct 6 2006, In : Biochemical and Biophysical Research Communications. 348, 4, p. 1272-1278 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Monoclonal antibody to human esophageal cancer endothelium inhibits angiogenesis and tumor growth

Zhang, Y., Ran, Y., Yu, L., Hu, H., Zhou, Z., Sun, L., Lou, J. & Yang, Z., Jul 1 2006, In : Anticancer research. 26, 4 B, p. 2963-2970 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Preparation of biocompatible magnetite nanocrystals for in vivo magnetic resonance detection of cancer

Hu, F., Wei, L., Zhou, Z., Ran, Y., Li, Z. & Gao, M., Oct 4 2006, In : Advanced Materials. 18, 19, p. 2553-2556 4 p.

Research output: Contribution to journalArticle

372 Scopus citations

Preparation of bioconjugates of CdTe nanocrystals for cancer marker detection

Hu, F., Ran, Y., Zhou, Z. & Gao, M., Jun 28 2006, In : Nanotechnology. 17, 12, p. 2972-2977 6 p., 025.

Research output: Contribution to journalArticle

43 Scopus citations

The correlation between adhesion of human cancer cells and microvesscular endothelium and organ-specific metastasis

Zhuan, Z., Long, Y. & Yuliang, R., Dec 1 2006, In : Chinese Journal of Clinical Oncology. 33, 21, p. 1-4 4 p.

Research output: Contribution to journalArticle

2004

Construction of human liver cancer vascular endothelium cDNA expression library and screening of the endothelium-associated antigen genes

Zhong, X., Ran, Y. L., Lou, J. N., Hu, D., Yu, L., Zhang, Y. S., Zhou, Z. & Yang, Z. H., May 15 2004, In : World Journal of Gastroenterology. 10, 10, p. 1402-1408 7 p.

Research output: Contribution to journalArticle

17 Scopus citations