• 1405 Citations
20042022
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Personal profile

Research Interests

Dr. Zhang’s translational imaging laboratory (80% effort) at the Robert H. Lurie Comprehensive Cancer Center has all the state-of-the art equipment for cancer research. Dr. Zhang’s research focuses on novel image-guided cancer immunotherapy including natural killer and dendritic cell-based immunotherapy, image-guided small molecular inhibitor and antibody immunotherapy, image-guided combination therapies of local ablation and targeted immunotherapy, image-guided drug delivery for cancer. Zhang team works on rabbit, mouse and rat tumor models to optimize and develop MRI sequences for the assessment of therapeutic response. Dr. Zhang joined the Quantitative Imaging Core Lab (QICL, 20% effort) of Northwestern University for clinical trials since March, 2014. As Manager of Quality and Regulatory Affairs of QICL, Dr. Zhang been working with Dr. Vahid Yaghmai in setting up business models as well as drafting necessary documentations including Imaging Protocol Development, Imaging Acquisition Site Credentialing and Training, Quality Control (QC) protocol, and Image Analysis and Interpretation. QICL provides a comprehensive set of quantitative imaging services for clinical and research purposes, in particular in oncology and for evaluation of responses to cancer therapies. To date, the QICL has reviewed imaging protocols and analyzed images for over 100 industry- and investigator-initiated clinical trials. Under the guidance and leadership of Dr. Vahid Yaghmai, QICL will establish the most comprehensive solution to help execute efficient and effective imaging clinical phase 1-3 trials.

Education/Academic qualification

PhD, Fourth Military Medical University, China

… → 2002

MA, Xi'an Jiatong University

… → 1996

MD, Xi'an Jiatong University

… → 1988

Research interests

  • Cell Imaging
  • Clinical Trial Methodology
  • Colon / Rectal Cancer
  • Liver Cancer
  • Oncology
  • Pancreatic Cancer
  • Prostate Cancer
  • Radiology

Fingerprint Dive into the research topics where Zhuoli Zhang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 7 Similar Profiles
Magnetic Resonance Imaging Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Nanoparticles Medicine & Life Sciences
Tumors Chemical Compounds
Magnetic resonance Chemical Compounds
Liver Medicine & Life Sciences
Imaging techniques Chemical Compounds
Electroporation Medicine & Life Sciences

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Grants 2011 2022

Pancreatic Neoplasms
Immunotherapy
Dendritic Cells
Vaccines
Magnetic Resonance Imaging
Microspheres
Liver
Neoplasms
sorafenib
Liver Neoplasms
Electroporation
Liver
Neoplasms
Planning Techniques
Hot Temperature

Research Output 2004 2019

  • 1405 Citations
  • 102 Article
  • 8 Review article
  • 1 Conference contribution

Association of radiomic imaging features and gene expression profile as prognostic factors in pancreatic ductal adenocarcinoma

Li, K., Xiao, J., Yang, J., Li, M., Xiong, X., Nian, Y., Qiao, L., Wang, H., Eresen, A., Zhang, Z., Hu, X., Wang, J. & Chen, W., Jan 1 2019, In : American Journal of Translational Research. 11, 7, p. 4491-4499 9 p., AJTR0097441.

Research output: Contribution to journalArticle

Transcriptome
Gene expression
Adenocarcinoma
Imaging techniques
Survival

Diffusion-Weighted MR Imaging to Evaluate Immediate Response to Irreversible Electroporation in a Rabbit VX2 Liver Tumor Model

Hu, S., Sun, C., Wang, B., Zhou, K., Pan, L., Shangguan, J., Yang, J., Yaghmai, V., Figini, M. & Zhang, Z., Jan 1 2019, (Accepted/In press) In : Journal of Vascular and Interventional Radiology.

Research output: Contribution to journalArticle

Electroporation
Rabbits
Liver
Neoplasms
Apoptosis

Gastrointestinal stromal tumor risk classification: spectral CT quantitative parameters

Zhang, X., Bai, L., Wang, D., Huang, X., Wei, J., Zhang, W., Zhang, Z. & Zhou, J., Jul 15 2019, In : Abdominal Radiology. 44, 7, p. 2329-2336 8 p.

Research output: Contribution to journalArticle

Gastrointestinal Stromal Tumors
Iodine
Research Ethics Committees

Iron-Oxide Nanocluster Labeling of Clostridium novyi-NT Spores for MR Imaging–Monitored Locoregional Delivery to Liver Tumors in Rat and Rabbit Models

Ji, J., Park, W. R., Cho, S., Yang, Y., Li, W., Harris, K., Huang, X., Gu, S., Kim, D-H., Zhang, Z. & Larson, A. C., Jul 1 2019, In : Journal of Vascular and Interventional Radiology. 30, 7, p. 1106-1115.e1

Research output: Contribution to journalArticle

Clostridium
Spores
Magnetic Resonance Spectroscopy
Rabbits
Liver

MYH9 promotes growth and metastasis via activation of MAPK/AKT signaling in colorectal cancer

Wang, B., Qi, X., Liu, J., Zhou, R., Lin, C., Shangguan, J., Zhang, Z., Zhao, L. & Li, G., Jan 1 2019, In : Journal of Cancer. 10, 4, p. 874-884 11 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Neoplasm Metastasis
Growth
Cell Movement
Nonmuscle Myosin Type IIA