• 1554 Citations

Research output per year

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Personal profile

Research Interests

Dr. Zhang’s translational imaging laboratory (80% effort) at the Robert H. Lurie Comprehensive Cancer Center has all the state-of-the art equipment for cancer research. Dr. Zhang’s research focuses on novel image-guided cancer immunotherapy including natural killer and dendritic cell-based immunotherapy, image-guided small molecular inhibitor and antibody immunotherapy, image-guided combination therapies of local ablation and targeted immunotherapy, image-guided drug delivery for cancer. Zhang team works on rabbit, mouse and rat tumor models to optimize and develop MRI sequences for the assessment of therapeutic response. Dr. Zhang joined the Quantitative Imaging Core Lab (QICL, 20% effort) of Northwestern University for clinical trials since March, 2014. As Manager of Quality and Regulatory Affairs of QICL, Dr. Zhang been working with Dr. Vahid Yaghmai in setting up business models as well as drafting necessary documentations including Imaging Protocol Development, Imaging Acquisition Site Credentialing and Training, Quality Control (QC) protocol, and Image Analysis and Interpretation. QICL provides a comprehensive set of quantitative imaging services for clinical and research purposes, in particular in oncology and for evaluation of responses to cancer therapies. To date, the QICL has reviewed imaging protocols and analyzed images for over 100 industry- and investigator-initiated clinical trials. Under the guidance and leadership of Dr. Vahid Yaghmai, QICL will establish the most comprehensive solution to help execute efficient and effective imaging clinical phase 1-3 trials.

Education/Academic qualification

PhD, Fourth Military Medical University

… → 2002

MA, Xi'an Jiatong University

… → 1996

MD, Xi'an Jiatong University

… → 1988

Research interests

  • Cell Imaging
  • Clinical Trial Methodology
  • Colon / Rectal Cancer
  • Liver Cancer
  • Oncology
  • Pancreatic Cancer
  • Prostate Cancer
  • Radiology

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  • Research Output

    • 1554 Citations
    • 106 Article
    • 8 Review article
    • 1 Conference contribution

    Association of radiomic imaging features and gene expression profile as prognostic factors in pancreatic ductal adenocarcinoma

    Li, K., Xiao, J., Yang, J., Li, M., Xiong, X., Nian, Y., Qiao, L., Wang, H., Eresen, A., Zhang, Z., Hu, X., Wang, J. & Chen, W., Jan 1 2019, In : American Journal of Translational Research. 11, 7, p. 4491-4499 9 p., AJTR0097441.

    Research output: Contribution to journalArticle

  • Dendritic cells in pancreatic cancer immunotherapy: Vaccines and combination immunotherapies

    Yang, J., Shangguan, J., Eresen, A., Li, Y., Wang, J. & Zhang, Z., Dec 2019, In : Pathology Research and Practice. 215, 12, 152691.

    Research output: Contribution to journalReview article

  • Diffusion-Weighted MR Imaging to Evaluate Immediate Response to Irreversible Electroporation in a Rabbit VX2 Liver Tumor Model

    Hu, S., Sun, C., Wang, B., Zhou, K., Pan, L., Shangguan, J., Yang, J., Yaghmai, V., Figini, M. & Zhang, Z., Nov 2019, In : Journal of Vascular and Interventional Radiology. 30, 11, p. 1863-1869 7 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Energy spectrum computed tomography improves the differentiation between benign and malignant solitary pulmonary nodules

    Zhao, J., Chai, Y., Zhou, J., Zhang, Z. & Wang, Z., Jan 1 2019, In : Clinical and Investigative Medicine. 42, 3, p. E40-E46

    Research output: Contribution to journalArticle

  • Gastrointestinal stromal tumor risk classification: spectral CT quantitative parameters

    Zhang, X., Bai, L., Wang, D., Huang, X., Wei, J., Zhang, W., Zhang, Z. & Zhou, J., Jul 15 2019, In : Abdominal Radiology. 44, 7, p. 2329-2336 8 p.

    Research output: Contribution to journalArticle