A Multi-Center Group to Study Acute Liver Failure

Project: Research project


The main purpose of this study is to obtain information about the course of the disease, samples of blood and possibly tissue samples from patients with acute liver failure. This condition is uncommon with approximately 2,000 cases a year in the United States. The variety of causes that lead to this massive liver injury include viruses, medications, poisoning and insufficient blood flow to the liver. Some patients do not have an identifiable cause for their disease. Since the condition is uncommon, it has been difficult to collect data concerning U.S. patients suffering from this condition. The present study will allow an in-depth analysis of cases of acute liver failure from centers around the United States, with an emphasis on the cause, and eventually, on the treatment of this puzzling yet devastating condition.
Effective start/end date9/16/158/31/20


  • University of Texas Southwestern Medical Center at Dallas (GMO-161131//5U01DK058369-20)
  • National Institute of Diabetes, Digestive and Kidney Diseases (GMO-161131//5U01DK058369-20)


Acute Liver Failure
Hematologic Diseases
Wounds and Injuries