A Multi-Part, Phase I, Multi-Center, Open Label, Plus Expansion Clinical Trial of an Off-The-Shelf Neoantigen Heat Shock Protein Vaccine (rHSC-DIPGVax) in Combination with Checkpoint Blockade for the Treatment of Diffuse Intrinsic Pontine Glioma and Diffu

Project: Research project

Project Details

Description

Immune monitoring including cytokine profiling, flow cytometry for immune subsets, ELISPOT assays, T cell receptor sequencing -> all from blood samples at multiple time points AND multiplex immunohistochemistry on FFPE tumor tissue
StatusActive
Effective start/end date11/2/2111/2/24

Funding

  • Ann & Robert H. Lurie Children's Hospital of Chicago (Agmt 11/02/22)

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