This work will compare a control ACS sponge, an ACS sponge soaked with BMP-2-Binding Nanofibers, a non-specific (non-BMP-2-binding) NanoSlurry, and a BMP-2-binding NanoSlurry for delivery of ultra low dose rhBMP-2 in the rabbit PLF model (10ug rhBMP-2 per animal). Outcome measures will include serial radiography, fusion scoring via manual palpation, and quantification of new bone formation by microCT.
|Effective start/end date||7/26/17 → 7/25/20|
- Medtronic Sofamor Danek, Inc. (Agmt 7/26/17)
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