A Novel Approach to Phosphorus Lowering in Patients with Chronic Kidney Disease

Project: Research project

Project Details


Sodium bicarbonate, may help stabilize kidney function in patients with chronic kidney disease. However, the optimal dose for testing this possibility in a clinical trial is uncertain. The BASE pilot clinical trial will help determine the best dose of sodium bicarbonate to use in a future study that will test the long-term safety and efficacy of sodium bicarbonate as a treatment to preserve kidney function in individuals with chronic kidney disease. The two doses of sodium bicarbonate being tested are 0.5 and 0.8 mEq/kg-lean body weight (LBW) per day.
Effective start/end date1/1/174/30/19


  • Veterans Medical Research Foundation of San Diego (08649005-321072 // 5U01DK97093-05)
  • National Institute of Diabetes and Digestive and Kidney Diseases (08649005-321072 // 5U01DK97093-05)


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