A novel desmoglein-1/T ctex-1(dynein light chain) interaction in epidermis

Project: Research project

Project Details


Proper skin structure is crucial to protect humans from environmental stress. This project will examine how the “sticky” protein, desmoglein-1, that holds cells together and provides mechanical strength to skin, can also coordinate skin development and support its proper structure. Desmoglein-1 performs these functions via binding to Tctex-1 (a part of molecular motor) and reorganizing the cell’s cytoskeleton during multilayer skin formation.
Effective start/end date7/1/146/30/15


  • Dermatology Foundation (Letter dated 04/24/2014)


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