A Randomized Control Trial of Mesh Suture Repair Versus Traditional Suture Repair for Paraesophageal Hernia

Patients seeking laparoscopic paraesophageal hernia repair who meet the study’s criteria will be offered an opportunity to participate (Table 1). Participants will be randomized in 2:1 fashion for treatment with mesh suture or standard suture, respectively. We believe this allocation ratio will reduce the impact of a mesh suture-related ‘learning curve’ without significantly affecting the study’s power. Sample size (n=80) was calculated at 53 patients for the mesh suture group and 27 patients for the standard group, assuming a 10% drop out rate.