A randomized controlled trial of Vulvar fractionated CO2-Laser therapy with and without concomitant topical clobetasol propionate 0.05% ointment for treatment of Vulvar lichen sclerosus (VULVIE)

  • Mueller, Margaret G (PD/PI)
  • Mueller, Margaret G (PD/PI)

Project: Research project

Project Details


In this trial we will employ a gold-standard randomized double-blind placebo-controlled trial design to determine whether combining FxCO2-laser with the traditional therapy of clobetasol propionate 0.05% ointment (combined treatment) as compared to FxCO2-laser and placebo ointment (FxCO2-laser only) will improve treatment response in women undergoing FxCO2-laser for vulvar lichen sclerosus.
Effective start/end date7/1/216/30/24


  • MedStar Health Research Institute (Mueller AGMT 6/23/22 // Mueller AGMT 6/23/22)
  • Patty Brisben Foundation for Women's Sexual Health (Mueller AGMT 6/23/22 // Mueller AGMT 6/23/22)


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