ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

Project: Research project

Project Details


ALLFTD is a comprehensive study targeting most varieties of FTLD. The overall goal of ALLFTD is to prepare for treatment trials in FTLD by focusing on several major activities:
1. Assemble a large group of well-characterized familial and sporadic FTLD patients evaluated at expert FTLD centers who can potentially be available for treatment trials
2 Collect comprehensive cognitive and behavioral data, in addition to imaging, blood and cerebrospinal fluid, with the following goals:
a. Identify the best clinical and biomarker measures for following patients with FTLD in treatment trials
b. Identify clinical measurements and biomarkers indicating that a person at high risk of FTLD due to a genetic mutation will begin to have symptoms in a predictable amount of time
3. Share clinical data, images and biological samples from participants affected by FTLD with the scientific community to address additional scientific questions about FTLD
Effective start/end date9/15/196/30/24


  • Mayo Clinic (NOR-263134-01/PO #67509301// 5U19AG063911-02)
  • National Institute on Aging (NOR-263134-01/PO #67509301// 5U19AG063911-02)


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