Autophagy-facilitated secretion in metabolic maintenance

Project: Research project

Project Details

Description

The goal of this proposal is to demonstrate a novel non-degradative, non-cell autonomous, mechanism by which the autophagy machinery regulates metabolism. Although emerging evidence suggests that autophagy abnormality is implicated in metabolic dysfunction, the mechanism by which autophagy regulates insulin sensitivity is largely unknown.
StatusActive
Effective start/end date9/17/217/31/25

Funding

  • National Institute of Diabetes and Digestive and Kidney Diseases (5R01DK123447-04)

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