Keyphrases
Celastrol
100%
Neurodegenerative Diseases
100%
Heat Shock Response
60%
Molecular Chaperone
40%
Heat Shock Factor 1 (HSF1)
30%
Huntington's Disease
30%
Neurotoxicity
20%
Neuroblastoma SH-SY5Y Cells
20%
Mechanism of Action
20%
Chaperone
20%
Cellular Toxicity
20%
Environmental Stress
10%
Screening Program
10%
Gene Expression
10%
Synthetic Analogues
10%
Self-associates
10%
Small Molecules
10%
Molecular Mechanism
10%
Alzheimer's Disease
10%
Protein Chaperone
10%
Effective Compounds
10%
Tissue Culture Cells
10%
Protein Inclusions
10%
Reporter Assay
10%
Natural Products
10%
Therapeutic Intervention
10%
Hereditary Disease
10%
Binding Targets
10%
Hsp70 Chaperone
10%
Heat Shock Promoter
10%
Physiological Stress
10%
Protein Misfolding
10%
Neurodegeneration
10%
Biochemical Methods
10%
Intrinsic Properties
10%
Specific Intent
10%
Damaged Proteins
10%
Potential Therapy
10%
Chaperone Hsp90
10%
Sequester
10%
Molecular Biology Techniques
10%
Toxic Protein
10%
New Targets
10%
New Drugs
10%
Heat Shock Proteins
10%
Parkinson's Disease
10%
Human Tissue
10%
NINDS
10%
Protein Aggregates
10%
Protein Conformation
10%
New Therapies
10%
Novel Therapies
10%
Medicine and Dentistry
Celastrol
100%
Degenerative Disease
100%
Heat Shock Response
60%
Chaperone
60%
Huntington's Disease
20%
Neurotoxicity
20%
Diseases
20%
Tissue Culture Cell
10%
Heat Shock Protein
10%
Heat Shock Transcription Factor
10%
Promoter Region
10%
SH-SY5Y
10%
Genetic Disorder
10%
Neurodegeneration
10%
Protein Aggregate
10%
Protein Misfolding
10%
Alzheimer's Disease
10%
Human Tissue
10%
Parkinson's Disease
10%
Protein Conformation
10%
Natural Product
10%
Neuroblastoma Cell Line
10%
Amyotrophic Lateral Sclerosis
10%
Pharmacology, Toxicology and Pharmaceutical Science
Celastrol
100%
Degenerative Disease
100%
Chaperone
60%
Huntington Chorea
20%
Neurotoxicity
20%
Diseases
20%
Cell Culture
10%
Nerve Degeneration
10%
Natural Product
10%
Genetic Disorder
10%
Neuroblastoma
10%
Heat Shock Transcription Factor
10%
Heat Shock Protein
10%
Alzheimer's Disease
10%
Protein Aggregate
10%
Parkinson's Disease
10%
Amyotrophic Lateral Sclerosis
10%