Keyphrases
Amyotrophic Lateral Sclerosis
100%
Molecular Mechanism
100%
Motor Neuron
53%
Human Motor Neurons
20%
Endoplasmic Reticulum Stress (ER stress)
13%
Electrical Excitability
13%
Molecular Pathways
13%
Excitability
13%
Disease-causing mutations
13%
Sporadic mutations
6%
Soma Size
6%
Opener
6%
Isogenic
6%
Reprogramming Technology
6%
Functional Level
6%
Pathophysiological Mechanisms
6%
Survival Motor Neuron
6%
UBQLN2
6%
CHCHD10
6%
K+ Current
6%
SOD1 mutation
6%
Mitochondrial Alterations
6%
Mitochondrial Abnormalities
6%
Electric Behavior
6%
TAR DNA-binding Protein 43 (TDP-43)
6%
Optogenetic Stimulation
6%
Selective Vulnerability
6%
Genetic mutation
6%
Gene number
6%
Transcriptional Level
6%
Transcriptome
6%
Mutant SOD1
6%
Diverse Functions
6%
Healthy Controls
6%
Pathophysiology
6%
Patch Clamp
6%
Genetic Engineering
6%
Neurodegenerative Diseases
6%
Lower Motor Neuron
6%
Induced Pluripotent Stem Cells (iPSCs)
6%
Apoptosis
6%
Upper Motor Neuron
6%
Firing Pattern
6%
Induced Pluripotent Stem Cell Technology
6%
Cellular Response
6%
C9orf72
6%
Patient-centered
6%
Superoxide Dismutase 1 (SOD1)
6%
Biochemistry, Genetics and Molecular Biology
Genetics
100%
Motor Neuron
100%
Excitability
36%
SOD1
27%
Induced Pluripotent Stem Cell
18%
Endoplasmic Reticulum Stress
18%
FUS
9%
Patch Clamp
9%
Reprogramming
9%
Gene Mutation
9%
Electric Activity
9%
Potassium Current
9%
Optogenetics
9%
Survival of Motor Neuron
9%
UBQLN2
9%
Upper Motor Neuron
9%
Lower Motor Neuron
9%
C9orf72
9%
Transcriptome
9%
Carisoprodol
9%
Neuroscience
Amyotrophic Lateral Sclerosis
100%
Motor Neuron
80%
Excitability
26%
SOD1
20%
Endoplasmic Reticulum Stress
13%
Stem Cell
13%
Neurodegenerative Disorder
6%
Transcriptome
6%
Soma
6%
Upper Motor Neuron
6%
Reprogramming
6%
Lower Motor Neuron
6%
Potassium Current
6%
Gene Mutation
6%
Genetic Engineering
6%
Patch Clamp
6%
Optogenetics
6%
Carisoprodol
6%