Delivery of Nano-Tethered Therapies to Brain Metastases of Primary Breast Cancer Using a Cellular Trojan Horse

Project: Research project

Project Details


Hypothesis: Nanoshell-laden monocytes/macrophages carrying therapeutic cargo, e.g., lapatinib, will home in to intracranial metastatic deposits by crossing the blood-brain barrier following injection into the systemic circulation. Once reaching the metastases the cargo will be able to be released by near infrared irradiation of the nanoshells.
Effective start/end date9/15/139/14/16


  • U.S. Army Medical Research and Materiel Command (W81XWH-13-1-0341)


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