Project Details
Description
Hypothesis: Nanoshell-laden monocytes/macrophages carrying therapeutic cargo, e.g., lapatinib, will home in to intracranial metastatic deposits by crossing the blood-brain barrier following injection into the systemic circulation. Once reaching the metastases the cargo will be able to be released by near infrared irradiation of the nanoshells.
| Status | Finished |
|---|---|
| Effective start/end date | 9/15/13 → 9/14/16 |
Funding
- U.S. Army Medical Research and Materiel Command (W81XWH-13-1-0341)
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