In this study, we will utilize our BMP-2 direct binding nanogel (BMP-2PA) in conjunction with a DBM powder, to create a demineralized bone nanomatrix (DBN).This combination will harness the mechanical strength of the DBM as well as its additional source of growth factors, while retaining all the advantages that a nanomatrix provides. We believe this approach will lead to reproducible, exogenous growth factor-free fusion in a rat spinal arthrodesis model.
|Effective start/end date||5/1/14 → 7/31/15|
- Lumbar Spine Research Society (LSRS2014)
Intercellular Signaling Peptides and Proteins
Bone and Bones