Development of a multi-modal targeted nanotherapeutic to prevent restenosis in an atherosclerotic environment

Professor Stupp’s lab will design, synthesize, and characterize the peptide amphiphiles (PAs) for the proposed research. The lab will participate in the evaluation and troubleshooting with the UNC team of all the in vivo animal experiments and redesign the PAs as necessary. They will work closely with the Kibbe Lab to ensure PAs are of sufficient purity, have appropriate supramolecular properties, and are co-assembled correctly prior to use in biological testing. This will be done through hands-on work in the lab, as well as through mentorship of Core staff and Stupp Lab researchers.