This proposalbrings together leaders in metabolic profiling and computatioal medicine for analysis of multi-omics data , and leading European/US prospective cohorts with subclinical atherosclerosis measurements. We propose to apply untargeted metabolic profiling using both proton Nuclear Magnetic Resonance spectroscopy (1H NMR) and Mass Spectrometry (MS) to discover novel biomarkers for subclinical atherosclerosis in sored serum samples from 4,000 people, with validation in stored samples from a further 4,000 people.
|Effective start/end date||6/25/12 → 9/30/14|
- Imperial College London (305422)
- European Commission (305422)