Differential Reorganization of Synaptic Protein Content By Typical and Atypical Antipsychotic Drugs

  • Sanz-Clemente, Antonio (PD/PI)

Project: Research project

Project Details

Description

I will compare the total protein content, synaptic redistribution and post-translational modification state of synaptic fractions isolated from animals expressing impaired cognition (treated with a typical or atypical APD). The precise characterization of their molecular reorganization will likely identify novel pharmacological targets useful for the treatment of SZ.
StatusFinished
Effective start/end date1/15/161/14/18

Funding

  • Brain & Behavior Research Foundation (24133)

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