Keyphrases
Antidepressants
100%
Small Molecules
100%
Hyperpolarization-activated Cyclic nucleotide-gated Channel
100%
TRIP8b
63%
Major Depressive Disorder
36%
Specific Intent
27%
Fluorescence Polarization Assay
18%
In Silico Screening
18%
Screening Assays
18%
Secondary Assays
18%
Polarization Test
9%
Psychiatric Disease
9%
Probe Optimization
9%
Rational Series
9%
In Vitro Screening Assay
9%
Rhythmogenesis
9%
Immunocytochemistry
9%
Biochemical Assay
9%
Neuronal Integration
9%
Fluorescent Thermal Shift Assay
9%
Functional Activity
9%
AlphaScreen
9%
In Silico Methods
9%
Target Engagement
9%
Primary Screening
9%
Glutathione S-transferase Pull-down
9%
Orthogonal Assay
9%
Tetratricopeptide Repeat
9%
Monoamine Neurotransmitters
9%
Genomic Deletion
9%
Brain Pathways
9%
Brain Regions
9%
Neuronal Excitability
9%
Channel Function
9%
Auxiliary Subunit
9%
Cell-based
9%
X-ray Crystal Structure
9%
Interacting Proteins
9%
Central Nervous System
9%
Synaptic Input
9%
Rab8b
9%
Zinc
9%
New Therapeutics
9%
Electrophysiology
9%
Unmet Medical Need
9%
Fluorescence Polarization
9%
High-throughput
9%
Flow Cytometry
9%
Medicine and Dentistry
Cyclic Nucleotide
100%
Antidepressant
100%
Major Depressive Episode
50%
HCN Channel
37%
In Silico
37%
Fluorescence Polarization
37%
Glutathione S-Transferase
12%
High Throughput Screening
12%
Flow Cytometry
12%
Tetratricopeptide Repeat
12%
Brain Region
12%
Gene Deletion
12%
Central Nervous System
12%
In Vitro Screening
12%
Excitability
12%
Immunocytochemistry
12%
Electrophysiology
12%
Neurotransmitter
12%
Neuroscience
Cyclic Nucleotide
100%
Antidepressant
100%
Major Depressive Disorder
50%
HCN Channel
37%
Glutathione S-Transferase
12%
Immunocytochemistry
12%
Neuronal Integration
12%
Neurotransmitter
12%
Central Nervous System
12%
Gene Deletion
12%
Neuronal Excitability
12%
Tetratricopeptide Repeat
12%
In Vitro
12%
Cell-Based Assays
12%
Flow Cytometry
12%
Electrophysiology
12%