Distributed cell-free manufacturing of biologics-based medical countermeasures

Project: Research project

Project Details


Protein therapeutics offer a significant opportunity to treat a broad range of chemical and biological threat agents. However, the timeline for developing and manufacturing MCMs is long, putting both warfighters and civilians at risk of technological surprise. We collectively believe that cell-free protein expression—the synthesis of proteins in crude extracts without living intact cells—offers a compelling solution to the problem but is best advanced through a consortium-based approach to mitigate existing challenges. In addition to the military benefit, cell-free technology could enhance disaster responsiveness, allow timely response to emergent/pandemic threats, facilitate diagnostic development, and enable distributed biomanufacturing anywhere on earth and even beyond.
Effective start/end date12/16/222/15/27


  • Army Research Office (W911NF2320039 P00002)


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