Dopamine’s Role in the Striatal Ensemble Dynamics of Learned Actions

Project: Research project

Project Details

Description

Aim 1: Confirm that D1- and D2-SPN ensemble dynamics undergo distinct transformations during reinforcement learning.
Aim 2: Establish the inter-relation of striatal dopamine transmission and the transformations in D2-SPN ensemble dynamics associated with reinforcement learning.
Aim 3: Determine whether in vivo Ca2+ and immediate early gene (IEG) expression dynamics predict changes in the strength of excitatory synaptic connections in D2-SPNs.
StatusActive
Effective start/end date1/1/2012/31/22

Funding

  • Whitehall Foundation, Inc. (2019-12-70)

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