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DYRK1A is a novel target in B-Cell leukemia
Crispino, John D
(PD/PI)
Medicine, Hematology Oncology Division
Project
:
Research project
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Keyphrases
B-cell Leukemia
100%
DYRK1A
100%
Pre-B ALL
20%
DYRK1A Kinase
20%
Unbiased Approach
20%
Preclinical Data
20%
Kinase Inhibitor
20%
Caspase-9
20%
DYRK1A Inhibitor
20%
Novel Substrates
20%
Growth Inhibition
20%
Phase I Study
20%
Pharmacologic
20%
Malignant B Cells
20%
Phosphorylation
20%
Cell Death
20%
New Therapies
20%
Further Development
20%
Pharmacology, Toxicology and Pharmaceutical Science
Caspase 9
100%
B Cell Leukemia
100%
Phosphotransferase Inhibitor
100%
Biochemistry, Genetics and Molecular Biology
DYRK1A
100%
B Cell
100%
Growth Inhibition
14%
Cell Death
14%
Caspase-9
14%
Kinase
14%
Phosphotransferase
14%