Effect of Laparoscopic Sleeve Gastrectomy on Esophagogastric Junction Distensibility

Project: Research project

Project Details


Obesity has become one of the most pressing health epidemics in the US with significant associated comorbidities for the one-third of adults with a body-mass index (BMI) over 30kg/m2 and substantial economic consequences1. Bariatric surgery, with restrictive and/or malabsorptive components, has emerged as the most effective treatment modality to provide sustained reduction in excess body weight and resolution of medical comorbidities5. Recently, laparoscopic sleeve gastrectomy (LSG) has become an increasingly popular alternative to traditional roux-en-y gastric bypass (RYGB)6. Observational studies have provided conflicting reports regarding resolution versus development of gastroesophageal reflux disease (GERD) following LSG7. The small amount of existing physiologic data on the effect of LSG on the lower esophageal sphincter (LES), however, has shown significant reductions in resting pressure at the LES during post-operative manometric evaluation.
Effective start/end date11/1/1510/22/18


  • American Society for Metabolic and Bariatric Surgery (AGMT-10/01/15)


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