Engineering the translation apparatus for the synthesis of electronically active sequence-defined polymers

Project: Research project

Project Details


In this proposal, we will apply chemistry, polymer science, biochemistry, bioengineering, computational modeling, and evolutionary biology tools to engineer the translation apparatus for synthesis of conjugated SDPs via step-growth and condensation polymerization reactions. Our focus in this white paper is on SDPs based on the Knoevenagel condensation, a type of carbonyl addition reaction. The full proposal will describe approaches to other SDP families (e.g., SDPs derived from Julia-Kocienski olefination and transition metal mediated cross-coupling reactions).
Effective start/end date7/1/166/30/22


  • Army Research Office (W911NF-16-1-0372 P00015)


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