Evaluation of Acute Effects of Amantadine on Corticostriatal Synaptic Plasticity in a Mouse Model of L-DOPA-Induced Dyskinesia.

Project: Research project

Project Details

Description

The objective of this study is to evaluate the acute effect of amantadine HCJ {AMT) on corticostriatal synaptic plasticity in the direct-and indirect-pathway spiny projection neurons (SPNs) in ex vivo brain slices from a mouse model of PD and L-DOPA-induced dyskinesia (LID).
StatusFinished
Effective start/end date2/1/1711/1/19

Funding

  • Adamas Pharmaceuticals, Inc. (Agmt 02/01/17)

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