Exploiting synthetic-lethal interactions to target triple-negative breast cancer

Project: Research project

Project Details


This proposed research is focused on better understanding and tackling triple-negative breast cancer (TNBC), for which currently no molecularly targeted therapeutic strategies are available. We will combine state-of-the-art preclinical experimental model systems and powerful bioinformatics approaches to identify ways to induce cell death selectively in triple-negative tumor cells while sparing non-tumorigenic cells.
Effective start/end date4/1/153/31/18


  • National Cancer Institute (5R00CA175700-05)


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