Exploring putative associations between thrombocytopenia and bromodomain modulation

Project: Research project

Project Details

Description

Summary
We propose a number of in vitro and in vivo experiments to assess the direct effect of BET compounds on the megakaryocyte lineage. We anticipate finding that the compound either induces apoptosis or impaired terminal maturation of megakaryocytes. Together, our studies will elucidate the biological and molecular effects of such compounds on the megakaryocyte lineage.
StatusFinished
Effective start/end date8/17/178/17/18

Funding

  • FORMA Therapeutics, Inc. (IS00006945)

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