Identifying Kawasaki Disease-Specific Antibodies and Antigens

Project: Research project

Description

In this proposal we will prepare KD-specific antibodies from these plasmablasts and use these antibodies as tools to detect KD-specific antigens. Identification of these antigens will provide important information about the etiology of KD and have a major impact on the field of pediatrics, by allowing for improved diagnosis, treatment, and prevention and reducing pediatric health care costs, morbidity, and mortality from the long-term consequences of childhood coronary artery aneurysms.
StatusActive
Effective start/end date7/1/194/30/20

Funding

  • Ann & Robert H. Lurie Children's Hospital of Chicago (901565-NU//7R21AI140029-03)
  • National Institute of Allergy and Infectious Diseases (901565-NU//7R21AI140029-03)

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Mucocutaneous Lymph Node Syndrome
Pediatrics
Coronary Aneurysm
Antigens
Antibodies
Health Care Costs
Coronary Vessels
Morbidity
Mortality