Imaging 360Degree View of the Schlemm’s Canal with Visible-Light Optical Coherence Tomography

Project: Research project

Description

By the year 2020, an estimated 80 million people worldwide will have glaucoma. Most diagnosis and treatment of glaucoma have been focused on lowering intraocular pressure. The Schlemm’s canal is a key component of the aqueous humor outflow pathway which helps regulate the intraocular pressure. While components of the aqueous humor outflow pathway prior to the Schlemm’s canal have been well-studied, the effects of post-Schlemm’s canal components on aqueous humor resistance are still not well understood. We will develop a visible-light OCT system capable of imaging the entire 360˚ of the SC and quantify structural changes in the SC during blood reflux in glaucomatous and control mice.
StatusFinished
Effective start/end date7/1/186/30/19

Funding

  • Illinois Society for the Prevention of Blindness (Letter 6/7/18)

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Aqueous Humor
Optical Coherence Tomography
Intraocular Pressure
Light
Glaucoma