By the year 2020, an estimated 80 million people worldwide will have glaucoma. Most diagnosis and treatment of glaucoma have been focused on lowering intraocular pressure. The Schlemm’s canal is a key component of the aqueous humor outflow pathway which helps regulate the intraocular pressure. While components of the aqueous humor outflow pathway prior to the Schlemm’s canal have been well-studied, the effects of post-Schlemm’s canal components on aqueous humor resistance are still not well understood. We will develop a visible-light OCT system capable of imaging the entire 360˚ of the SC and quantify structural changes in the SC during blood reflux in glaucomatous and control mice.
|Effective start/end date||7/1/18 → 6/30/19|
- Illinois Society for the Prevention of Blindness (Letter 6/7/18)
Optical Coherence Tomography