In Vivo Evaluation of 3D-Printed Electroconductive Graphene Composites for Osteogenic, Myogenic, and Neurogenic Regeneration

Project: Research project

Project Details

Description

Children born with craniofacial microsomia may
experience a spectrum of abnormalities ranging from maxillary
and mandibular hypoplasia, complex microtia and hearing loss,
and facial palsy. The 3-dimensional and functional complexity of
reconstruction of multiple tissue types have led to our overall
objective to study the in vivo potential of 3D-printed,
electroconductive, graphene for osteogenic, myogenic, and
neurogenic tissue engineering. By utilizing a versatile 3D-ink
technology based on a common polymer base, we aim to study
the effects of graphene-hydroxyapatite and graphene-muscle
derived extracellular matrix (ECM) material composites on in vivo
biocompatibility and tissue differentiation.
StatusFinished
Effective start/end date1/1/178/31/18

Funding

  • Maxillofacial Surgeons Foundation (MAXILLOFICIAL SURGEONS FND 9/25/16)

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