IPA for Victorson: Measuring Quality of Life in Veterans with Deployment-Related PTSD

Project: Research project

Project Details


This project will result in the development of improved measures of health related quality of life
(HRQOL) for veterans with post traumatic stress disorder (PTSD). Because our work will be built on
and linked to work of larger national HRQOL projects, the results will not only improve measurement
for veterans with PTSD but will also allow for comparison of results across clinic settings and
disease groups. We will develop and validate a short form of the measure that will enable using it
traditional self-administered techniques. In addition, algorithms will be created to facilitate the
adaptation of the resultant measures into a computerized adapted testing (CAT) environment, which
will streamline the use of the tool in clinical practice and reduce respondent burden.

While the primary outcome measure used to test the efficacy of clinical interventions in PTSD is
the reduction of symptoms, increasingly measures of health related quality of life (HRQOL) are also
included. The most commonly used HRQOL measure employed in clinical studies of veterans with PTSD
is the Medical Outcomes Study Short Form Health Survey (SF-36). The SF-36 is a "generic" HRQOL
instrument that does not contain specific domains/items reflecting quality of life issues
experienced by veterans with deployment-related PTSD. The goal of this study is to design more
sensitive measures of deployment-related PTSD HRQOL for veterans that do contain such

The short term objectives of this study are to: 1) Identify the most important HRQOL issues,
concerns and subsequent domains/constructs (e.g. distress, pain, social role changes) that a HRQOL
measure should assess in Veterans with deployment-related PTSD. 2) Develop new items pools and/or
adapt item banks from existing NIH funded tools (e.g., PROMIS/Neuro QOL) that represent
Effective start/end date10/1/129/30/15


  • James A. Haley Veterans’ Hospital (673-D37039)


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