Knee OA is a major cause of pain, functional limitation and disability, but there are critical gaps in knowledge about the long-term clinical course of the disease and its determinants. We propose to extend the follow-up for knee OA outcomes in the entire Osteoarthritis Initiative Cohort from 8 to16 years in order to assess a broad range of long-term health outcomes of knee OA and to identify potentially modifiable predictors of poor and successful outcomes, using an approach that addresses important challenges in the study of disease progression.
|Effective start/end date||9/15/17 → 5/31/22|
- University of California, San Francisco (10477sc//R01AG050469)
- National Institute on Aging (10477sc//R01AG050469)