Longitudinal Relationships Among Sleep, Cognition and Alzheimer's Disease Biomarkers: Discerning Causal Associations, Mediators, and Susceptibility

Project: Research project

Project Details

Description

Response to PAR-19-070 (under PAR-18-596)

Title: Longitudinal Relationships Among Sleep, Cognition and Alzheimer’s Disease Biomarkers: Discerning Causal Associations, Mediators, and Susceptibility

Primary Principal Investigator: Susan Redline, MD, MPH
Primary Institution: Brigham and Women’s Hospital
Submission Date: November, 2020
Proposed dates of the project: April 1, 2021 – March 31, 2025

The Northwestern University Field Center, under the leadership of Dr. Norrina Allen, will:
• Participate in central training

• Complete certification/training requirements for this project

• Recruit approximately 300 MESA-MIND participants to the MESA-MIND-SLEEP exam over an approximately 2-year period.

• Conduct in-home visits to collect sleep and ambulatory blood pressure data

• Review and transmit data to the Sleep Reading Center/BWH

• Communicate study feedback, medical alerts to participants as needed

• Provide input into analyses and manuscripts
StatusActive
Effective start/end date5/1/212/28/25

Funding

  • Brigham and Women's Hospital (125298//1R01AG070867-01)
  • National Institute on Aging (125298//1R01AG070867-01)

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