Mapping and Exploiting the Subclonal Architecture of LungAdenocarcinoma

Project: Research project

Project Details

Description

Our research program is innovative because it
integrates large genomic datasets for recurrent alterations that confer therapeutic resistance and validates these
alterations as predictive diagnostics and therapeutic targets in laboratory and preclinical model systems. The
methods are unique to our group in so far as we are the first to use the information-based similarity metric to the
measure the mutual dependence between responses to DNA damaging agents and genetic features (12).
StatusFinished
Effective start/end date2/1/206/30/20

Funding

  • American Lung Association (AGMT 6/25/20)

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